A1TFL3
Gene name |
otsA |
Protein name |
Trehalose-6-phosphate synthase |
Names |
TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA |
Species |
Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii) |
KEGG Pathway |
mva:Mvan_5192 |
EC number |
2.4.1.15: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1TFL3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1TFL3-F1 | Predicted | AlphaFoldDB |
No variants for A1TFL3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1TFL3 | |||||
No associated diseases with A1TFL3
No regional properties for A1TFL3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A1TFL3 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.15 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity | Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP. |
| alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity | Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| trehalose biosynthetic process | The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPQSGPEAR | SGGADFVVVA | NRLPIDMVRR | ADGTTEFKRS | PGGLVTALEP | LLRRRHGAWI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GWPGVPEDAD | DPNAATEPIE | QDGMTLVPVR | LSSEDVAEYY | EGFSNATLWP | LYHDVIVKPI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YHREWWDRYV | DVNRRFAEAT | AHTAAEGATV | WVQDYQLQLV | PKMLRMLRPD | LTIGFFLHIP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FPPVELFMQM | PWRTEIIEGL | LGADLVGFHL | PGGAQNFLIL | ARRLIGATTS | RGNVGVRSRF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GEVQFGFRTV | KVGAFPISID | SAELDQHARS | RATRQRAKEI | RAELGNPRKI | LLGVDRLDYT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KGIDVRLRAF | SELLEEGRID | PEDTVLVQLA | TPSRERVESY | VAMREDIERQ | VGHVNGEFGE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VGHPVLHYLH | RPIPREDLVA | FFVAADVMLV | TPLRDGMNLV | AKEYVACRHD | LGGALVLSEF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TGAAAELRQA | YLTNPHHIEG | VKDAIEAALT | QAPEEGRRRM | RAMRRQVLAH | DVDRWARSFL |
| 490 | |||||
| DALASKEPVE | G |