A1S462

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
KEGG Pathway
saz:Sama_0961
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

12-321 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1S462

Entry ID Method Resolution Chain Position Source
AF-A1S462-F1 Predicted AlphaFoldDB

No variants for A1S462

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1S462

No associated diseases with A1S462

7 regional properties for A1S462

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 382 - 551 IPR000795
domain Small GTP-binding protein domain 386 - 540 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 47 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 305 - 355 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 59 - 97 IPR013575
domain Translation initiation factor IF- 2, domain 3 658 - 772 IPR023115
domain Translation initiation factor IF-2, domain II 558 - 651 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEITVEKLA TEVGKTVDRL IEQFAQAGIK KAKADTVSES EKQQLLDFLK KQHGADAQPT
70 80 90 100 110 120
KMTLQRKTVS TLSVSSGGGQ SKDVKVEVRK KRTFVKRDGN EAALKAEEEA RAQAEAQAKA
130 140 150 160 170 180
EAEAKAKAEA EAKAKADAEA KAKAKAEAEA KAKASASAAK EQPKPVESEE AKAEAARLKS
190 200 210 220 230 240
QQEEAAKSKA AQEEAAAKEK ARLLAEENAA RWAEEERRRI EAERYGDHHV TTSKVARAAE
250 260 270 280 290 300
DSADLDDEKR GRRNRNKTQT KSKRGGKDAR EGREKHMKYK STPESMAHGF NKPVAAVTRD
310 320 330 340 350 360
VRIGETVTVA ELAQKMAVKA TEIIKAMMKM GSMVTINQVL DQETAQLVAE EMGHKVVLLR
370 380 390 400 410 420
ENELEHQVLA DRDDEGTTKL EPRAPVVTIM GHVDHGKTSL LDYIRRTKVA AGEAGGITQH
430 440 450 460 470 480
IGAYHVETDN GMITFLDTPG HAAFTAMRAR GAKATDIVIL VVAADDGVMP QTIEAIQHAK
490 500 510 520 530 540
AGNVPLIVAV NKMDKPEADI DRVKNELSQH GVMSEDWGGE NMFCYVSAKT GQGVDELLEA
550 560 570 580 590 600
ILLQAEVLEL KAVRDGMAAG VVIESQLDKG RGPVATVLVQ EGTLRQGDIV LCGLEYGKIR
610 620 630 640 650 660
AMKDENGRPI MEAGPSIPVE ILGLSGVPSA GDEATVVRDE RKAREVALYR QGKFRDVKLA
670 680 690 700 710 720
RQQKSKLENM FANMTEGEVQ ELNIVLKADV QGSLEAITDS LRKLSTDEVK VNIIASGVGA
730 740 750 760 770 780
LTETDATLAA ASNAIMVGFN VRADAQARKT IESEAVDLRY YSVIYDLIDE VKSAMSGMLS
790 800 810 820 830 840
PEFKQQIIGL AEVRDVFKSP KLGAIAGCMV IEGIVKRSAP IRVLRENVVI YEGELESLRR
850 860 870 880
FKDDVNEVRN GMECGIGVKN YNDVRVGDQI EVFETIEVAR TL