A1RXH6
Gene name |
infB |
Protein name |
Probable translation initiation factor IF-2 |
Names |
|
Species |
Thermofilum pendens (strain DSM 2475 / Hrk 5) |
KEGG Pathway |
tpe:Tpen_0499 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1RXH6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1RXH6-F1 | Predicted | AlphaFoldDB |
No variants for A1RXH6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1RXH6 | |||||
No associated diseases with A1RXH6
5 regional properties for A1RXH6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 10 - 227 | IPR000795 |
| domain | Translation elongation factor EFTu-like, domain 2 | 252 - 330 | IPR004161 |
| domain | Small GTP-binding protein domain | 15 - 143 | IPR005225 |
| domain | Translation initiation factor IF- 2, domain 3 | 343 - 450 | IPR023115 |
| domain | Elongation factor Tu-type domain | 472 - 557 | IPR029459 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNDQGSQFL | RAPIVVVLGH | VDAGKTTLLD | KIRGTAVAKR | EPGTMTQHIG | ASFLPWKALE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AVCGSLVSQI | RAEVVIPGFL | VIDTPGHEAF | SNLRRRGGSI | ADIAILVVDV | LRGLEQQTFE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SIDILRERKV | PFIVAVNKID | KIPGWKSFPN | TPFVESVKRQ | SEAAQLKLEE | LLSYIIQQFA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SLGFRSDRYD | RIRDFTRVLA | LVPVSAVTGE | GIPDLLLVLA | GLAQRYLKGR | LLASIAPGKG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VILELKEEAG | LGMTATLILY | DGVIRRGDIV | VTGGIEGAFS | TRVRALLMPK | PLDEMRSPED |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RFLEVERIVA | AAGVKLVAEG | LEKAVPGAPL | FVAVSEEEVG | RLKQLVEEEI | SGVKFERDVV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GVVVKADTLG | TLEALVGYLK | KQGIPIRVAD | IGPVVKRDVV | QASMVKEKDP | LYAAILAFNV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KILPEAQDEA | ARHGIPVFQE | RIMYKLVENY | QKWLQETRDA | EVRKAFEKIT | PPAVVQILPG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YVFRRRDPII | VGVRVVCGRI | RSGVPLITKD | GREIGEIMQI | KEHDKVLDVV | SEGAEVAISI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RSKAIVGRQV | KEGDYLYSNL | SIEEINRLLE | KYEKYLAENE | KSYLRKLMRF | KMGLSKEIEY |
| P |