A1RX88

PR
Gene name
eIF5A (Tpen_0409)
Protein name
Translation initiation factor 5A
Names
Hypusine-containing protein, eIF-5A
Species
Thermofilum pendens (strain DSM 2475 / Hrk 5)
KEGG Pathway
tpe:Tpen_0409
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

70-132 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1RX88

Entry ID Method Resolution Chain Position Source
AF-A1RX88-F1 Predicted AlphaFoldDB

No variants for A1RX88

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1RX88

No associated diseases with A1RX88

2 regional properties for A1RX88

Type Name Position InterPro Accession
domain Proteasome component (PCI) domain 218 - 404 IPR000717
domain Eukaryotic translation initiation factor 3 subunit E, N-terminal 5 - 135 IPR019010

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ribosome binding Binding to a ribosome.
RNA binding Binding to an RNA molecule or a portion thereof.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

2 GO annotations of biological process

Name Definition
positive regulation of translational elongation Any process that activates or increases the frequency, rate or extent of translational elongation.
positive regulation of translational termination Any process that activates or increases the frequency, rate or extent of translational termination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTRPEEAGN IKVGSFIVID GEPCKVVEVE KSKTGKHGSA KARIVGIGFF DGGKRSIVVP
70 80 90 100 110 120
TDARVEVPII KKFTAQVVAF VGDNVQLMNL EDYSTFEIPM PQEEEIKSKL SEGVEVEVWE
130
VMGRHKIMRV RA