A1KU93
Gene name |
ttcA |
Protein name |
tRNA-cytidine(32) 2-sulfurtransferase |
Names |
Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA |
Species |
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18) |
KEGG Pathway |
nmc:NMC1192 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1KU93
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1KU93-F1 | Predicted | AlphaFoldDB |
No variants for A1KU93
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1KU93 | |||||
No associated diseases with A1KU93
3 regional properties for A1KU93
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translation elongation factor EFTs/EF1B, dimerisation | 71 - 323 | IPR014039 |
| conserved_site | Translation elongation factor Ts, conserved site | 12 - 27 | IPR018101-1 |
| conserved_site | Translation elongation factor Ts, conserved site | 75 - 85 | IPR018101-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4 iron, 4 sulfur cluster binding | Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| sulfurtransferase activity | Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). |
| tRNA binding | Binding to a transfer RNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA thio-modification | The addition a sulfur atom to a nucleotide in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKKTKQELE | NNKLSKRLRH | AVGDAINDFN | MIEPDDKIMV | CLSGGKDSYA | LLDILRQLQA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SAPIDFELVA | VNLDQKQPGF | PEEVLPTYLE | SIGVPYKIVE | EDTYSTVKRV | LDEGKTTCSL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CSRLRRGILY | RTAKELGCTK | IALGHHRDDI | LATMFLNMFY | GGKLKAMPPK | LVSDNGEHIV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IRPLAYVKEK | DLIKYAELKQ | FPIIPCNLCG | SQPNLQRQVI | GDMLRDWDKR | FPGRIESMFS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALQNVVPSHL | ADTELFDFAG | LERGQTLKHG | GDLAFDSEKM | PERFSDGSEE | DESEIKIAPQ |
| 310 | |||||
| KAERKVINIL | ANKPKTCGA |