A1KU16

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)
KEGG Pathway
nmc:NMC1104
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1KU16

Entry ID Method Resolution Chain Position Source
AF-A1KU16-F1 Predicted AlphaFoldDB

No variants for A1KU16

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1KU16

No associated diseases with A1KU16

5 regional properties for A1KU16

Type Name Position InterPro Accession
domain ACT domain 673 - 757 IPR002912-1
domain ACT domain 785 - 852 IPR002912-2
domain HD/PDEase domain 432 - 585 IPR003607
domain HD domain 436 - 558 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 161 - 299 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPANLSSALE TFKQQRDAAE AHYLKTNRVS VFFREYTAAV ETLLAALWVE HFQNSALCLM
70 80 90 100 110 120
AVGGFGRGEL YPCSDVDLAV VSPAPLSDGI QEQIARFVQT LWDCKLMPSV KSGGIDELCE
130 140 150 160 170 180
SVRNDITGDT AFLEARFLFG NRQTADELAE KMNAQRNVAA FIEAKLVEME HRHAKSQGSG
190 200 210 220 230 240
AVLEPNIKSC PGGLRDIHTL LWIAKAQGLA TNLPALVKQG ILTRTEAGML SHGYRRLAHI
250 260 270 280 290 300
RIHLHLNAKR AEDRLLFDLQ PQVAESMGYQ GLNLRRQSEE LMRVFYRAIK TVKQLSGILT
310 320 330 340 350 360
PMLQSRVSST PLRVTLRIDD DYIQVNNQIA ARHTDIFFRR PEHIFKIVEI MQQRNDITAL
370 380 390 400 410 420
EPQTLRAWWG ATRKINRSFY QNSENRHRFA GFFRNGNGLT QTLRFLNLYG VLGRYLPAWE
430 440 450 460 470 480
KIVGLLQHDL FHIYPVDDHI LTVVRNVRRL ALDMHSHELP YASALMQSFE RQDILYLAAF
490 500 510 520 530 540
FHDIAKGRGG DHAIQGIADA RQFAADHFLT EEESDLLAWL VENHLLMSTV AQKEDIQDPS
550 560 570 580 590 600
VLDAFCKRVQ THERLSALYL LTISDIRGTN PKLWNAWRAS LLESLFHAAG RYLAGNGGNP
610 620 630 640 650 660
HALFGRRQQE AADLLTRAAV PEKQQKKLWN ALGSAYFARH QSREILWHAA NLVHDFETPI
670 680 690 700 710 720
VRSRILPQSD SFQVMVFMPN GPRLFARLCR IFSRHGFDIL AARAFITEHD YILDTFIVQI
730 740 750 760 770 780
PSQHAPEDYP DIQSALEAEL NSFIHGHTVA EISSHSRRIS RRSRYMPIAP SITITPEEDY
790 800 810 820 830 840
PDWYSVEITA VNRPFLLADM AEIFFAHNVS LRYAKISTLD ERAEDSFTVF SPDLKNPKIQ
850
SSLKQALLEQ LA