A1K6Q8

PR
Gene name
lpxB
Protein name
Lipid-A-disaccharide synthase
Names
Species
Azoarcus sp (strain BH72)
KEGG Pathway
azo:azo1896
EC number
2.4.1.182: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

334-391 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1K6Q8

Entry ID Method Resolution Chain Position Source
AF-A1K6Q8-F1 Predicted AlphaFoldDB

No variants for A1K6Q8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1K6Q8

No associated diseases with A1K6Q8

No regional properties for A1K6Q8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A1K6Q8

Functions

Description
EC Number 2.4.1.182 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
lipid-A-disaccharide synthase activity Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP.

1 GO annotations of biological process

Name Definition
lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPRIAMVAG EASGDLLASH LIRAIRARVP DAEFFGIGGP KMQAEGFDAR WPCELLAVHG
70 80 90 100 110 120
YVDALKRYRE LSGIRKKLLK QVRRERPDAF IGVDAPDFNL WLEGKIKAAG IPAIHFVSPS
130 140 150 160 170 180
IWAWRGGRIK RIARSVTRML CMFPFEPELY ERAGVPVSYV GHPLADVFPL EPDRAAARER
190 200 210 220 230 240
LDIAPERKVV ALLPGSRQSE VRNLGELFIE TAAMLAQRHP DVLFLVPLAT RETRELFSAA
250 260 270 280 290 300
LARNKGDELP LRMLFGHAVD AMTAADAVLV ASGTASLEAA LLKRPMVITY RMGKWQYRLM
310 320 330 340 350 360
KRMAYLPWIG LPNILCREGL VPELVQDDAT PPKLADALER WLVDPAACAA LTERFTALHH
370 380 390
SLRQNTAEKA AAAVLPYLSS SASCQPVSVS A