A1JTL6
Gene name |
argG |
Protein name |
Argininosuccinate synthase |
Names |
Citrulline--aspartate ligase |
Species |
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) |
KEGG Pathway |
yen:YE2680 |
EC number |
6.3.4.5: Other carbon--nitrogen ligases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1JTL6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1JTL6-F1 | Predicted | AlphaFoldDB |
No variants for A1JTL6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1JTL6 | |||||
No associated diseases with A1JTL6
2 regional properties for A1JTL6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Argininosuccinate synthase, conserved site | 17 - 25 | IPR018223-1 |
| conserved_site | Argininosuccinate synthase, conserved site | 129 - 140 | IPR018223-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.4.5 | Other carbon--nitrogen ligases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| argininosuccinate synthase activity | Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| arginine biosynthetic process | The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTILKHLPI | NQRVGIAFSG | GLDTSAALLW | MQKKGAIPYA | YTANLGQPDE | EDYDAIPRKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MEYGAEKARL | IDCRKQLVAE | GIAAIQCGAF | HNTTAGVTYF | NTTPLGRAVT | GTMLVAAMKE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGVNIWGDGS | TYKGNDIERF | YRYGLLTNAE | LKIYKPWLDT | DFIDELGGRH | EMSEFMIQSG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FDYKMSTEKA | YSTDSNMLGA | THEAKDLEFL | NSSVKIVNPI | MGVKFWDENV | VVKAEEVSVR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FERGYPVALN | GVVFDDSVEL | MMEANRIGGR | HGLGMSDQIE | NRIIEAKSRG | IYEAPGMALL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HIAYERLLTG | IHNEDTIEQY | HANGRVLGRL | LYQGRWFDPQ | ALMLRDSAQR | WVASEITGEV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TLELRRGNDY | SILNTVSENL | TYQPERLTME | KGDSVFSPDD | RIGQLTMRNL | DITDTRKKLF |
| 430 | 440 | 450 | |||
| SYATTGLLSA | SAEVGLPQVD | NNNLTARGLQ | DKSK |