A1JIG5

PR
Gene name
pepQ
Protein name
Xaa-Pro dipeptidase
Names
X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase
Species
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
KEGG Pathway
yen:YE0269
EC number
3.4.13.9: Dipeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1JIG5

Entry ID Method Resolution Chain Position Source
AF-A1JIG5-F1 Predicted AlphaFoldDB

No variants for A1JIG5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1JIG5

No associated diseases with A1JIG5

2 regional properties for A1JIG5

Type Name Position InterPro Accession
domain Peptidase M24 168 - 436 IPR000994
conserved_site Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site 341 - 353 IPR001131

Functions

Description
EC Number 3.4.13.9 Dipeptidases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
phosphoric triester hydrolase activity Catalysis of the hydrolysis of a phosphoric triester.
proline dipeptidase activity Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
METLASLYNE HLSTLQQRTR DVLERHQLDA LLIHSGELQR IFLDDRDYPF KVNAQFKAWV
70 80 90 100 110 120
PVTQVPNCWL WVDGVNTPKL WFYSPVDYWH CVEPLPDSFW TKAIDIQPLV NANDIAQLLP
130 140 150 160 170 180
VQRERVAYIG YAQQRAQALG FSAENINPKP VLDYLHFYRS YKTDYELACM REAQKTAVAG
190 200 210 220 230 240
HNAAHEAFLS GMSEFDINLA YLMATGQRDT DVPYDNIVAL NEHSAVLHYT TLQHQPPAEI
250 260 270 280 290 300
RSFLIDAGAE YNGYAADLTR TYVAGSKNTA DSKNDFAALI KDLNNEQLGL IKTLKCGVNY
310 320 330 340 350 360
TEYNVQMHQR IAKLLRTHNL VTGISEEAMV EQGITCPFLP HGLGHPLGLQ VHDTAGFMQD
370 380 390 400 410 420
DKGAHLSAPS KYPYLRCTRI LQPRMVLTIE PGLYFIESLL APWRSGEFSQ HFNWDLIETL
430 440
KPYGGIRIED NIVIHENRVE NMTRDLKLA