Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A1D3V8

Entry ID Method Resolution Chain Position Source
AF-A1D3V8-F1 Predicted AlphaFoldDB

No variants for A1D3V8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1D3V8

No associated diseases with A1D3V8

9 regional properties for A1D3V8

Type Name Position InterPro Accession
domain Helicase, C-terminal 424 - 621 IPR001650
conserved_site SEC-C motif 893 - 910 IPR004027
domain SecA DEAD-like, N-terminal 6 - 389 IPR011115
domain SecA Wing/Scaffold 612 - 822 IPR011116
domain SecA, preprotein cross-linking domain 228 - 345 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 248 IPR014001
domain SecA motor DEAD 3 - 613 IPR014018
conserved_site SecA conserved site 487 - 502 IPR020937
domain SecA, C-terminal helicase domain 407 - 583 IPR044722

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cellular response to glucose starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
regulation of mitotic metaphase/anaphase transition Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADLQNLEAV ADHPNGSAIA SPRSSTDSRS PSTRSQSLRL NHSNHQHRQS FSESLRAAPG
70 80 90 100 110 120
SPRTRRQPSF TQAAIQSLID NPPAPKDVNP AFAGRDWREI SIGELVRPDD LRFVELDTGI
130 140 150 160 170 180
EEATNTLIDS DAPVLLIRET PEHKTAVGTF DYSDLNAYLL LAAGLTQPNE ELRESYEELA
190 200 210 220 230 240
RKARDEHKIP LKDVKELSRS EPLTTLPASA NLMTAVETFG GGVHRVVVVD EHNNGEVVGI
250 260 270 280 290 300
VSQFRLVKFL WENGRSFPVI DQLYPQYLRD LGIGSREVIS INGDKQLCEA LQIMNSEGIS
310 320 330 340 350 360
SIAVVDNHSN VVGNISTTDV KLLTRSSSLP LLHNTCIHFI SVILSARGLI EGKDSFPVFY
370 380 390 400 410 420
VNPSSTLAHT VAKMVATKSH RLWVTDPLSP SSSGPPTPSH SSVQLPLAAS TNSTQSPPVS
430 440 450 460 470 480
PPATTTNLPA PNYSTPHLPS PPQPFMNAAS LTHPAASVGM PHGVAPSIPA SALPGARLSG
490 500 510 520 530
RLVGVVSLTD ILNLHARASG LSPADPAESR SRRRRSSSSS VSVRKSGDIG RELFSRRD