A1D3F5
Gene name |
erb1 (NFIA_016440) |
Protein name |
Ribosome biogenesis protein erb1 |
Names |
Eukaryotic ribosome biogenesis protein 1 |
Species |
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus) |
KEGG Pathway |
nfi:NFIA_016440 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1D3F5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1D3F5-F1 | Predicted | AlphaFoldDB |
No variants for A1D3F5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1D3F5 | |||||
No associated diseases with A1D3F5
14 regional properties for A1D3F5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 39 - 84 | IPR001680-1 |
| repeat | WD40 repeat | 89 - 125 | IPR001680-2 |
| repeat | WD40 repeat | 180 - 224 | IPR001680-3 |
| repeat | WD40 repeat | 257 - 296 | IPR001680-4 |
| repeat | WD40 repeat | 315 - 354 | IPR001680-5 |
| repeat | WD40 repeat | 359 - 398 | IPR001680-6 |
| repeat | WD40 repeat | 520 - 564 | IPR001680-7 |
| repeat | WD40 repeat | 567 - 606 | IPR001680-8 |
| repeat | WD40 repeat | 613 - 663 | IPR001680-9 |
| repeat | WD40 repeat | 660 - 702 | IPR001680-10 |
| conserved_site | WD40 repeat, conserved site | 209 - 223 | IPR019775 |
| repeat | G-protein beta WD-40 repeat | 71 - 85 | IPR020472-1 |
| repeat | G-protein beta WD-40 repeat | 209 - 223 | IPR020472-2 |
| repeat | G-protein beta WD-40 repeat | 641 - 655 | IPR020472-3 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| PeBoW complex | A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| large ribosomal subunit rRNA binding | Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA. |
| ribonucleoprotein complex binding | Binding to a complex of RNA and protein. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNGSKASKKR | KAVTRDVEEE | AGVFSGDELN | TDNLDGALSD | NANDLSSDED | ESDSEVELID |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DFSDEDDEEE | EDVLDSDEIP | SDGEDLAKKK | SNTAPGELGA | AMDDGESSSE | GEQLNYRIEK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DANGNDRFVY | DEINPDDNSE | YSDIEENANT | IGDIPLSFYD | QYPHIGYDIN | GKKILRPAKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EALDALLDSI | EIPKGWTGLT | DPSTGKPLEL | SQEELELLRK | VQMNEIPEDG | YNPYEPTVEW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FTSQQEIMPL | SAAPEPKRRF | VPSKHEAKRV | MKIVKAIREG | RILPFKPPTE | EDEEDDTIIK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YDLWADEAER | KDHPMHIPAP | KLPPPGYEES | YHPPPEYLPS | QKERKAWEEA | DPEDRASEFL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PNDFGSLRRV | PGYENFVKEK | FERCLDLYLA | PRVRRSKLNI | DPESLLPKLP | SPEELKPFPT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ACATVFRGHK | GRVRTLAVDP | SGLLLATGGD | DGTVRVWELL | TGRQLWSVKL | SEEDPVNVVR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| WRPGKDALIL | AAAAGDDIFL | AVPPIVDPAI | EKASLDILDA | GWGYAASVPP | PTPAEANKKN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NPPKWMRPSS | SLADLGVCAV | IPLRYVAKSL | SWHRRGDYFV | TVCPGSSTPA | SVAIAIHTLS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KHLTQYPFRR | RIKGGGPPQA | AHFHPSKPIL | FVANQRSIRA | YDLSRQLLVK | ILQPGARWIS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SFDIHPTSST | ASGGDNLIVG | SYDRRLLWHD | LELSQRPYKT | LRYHRKAIRA | VKFHPGGRYP |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LFADASDDGS | LQIFHGSVTG | DMLSNATIVP | LKVLKGHKIT | GELGVLDVDW | HPREPWCVSA |
| GADGTCRLWM |