A1CYR9

PR
Gene name
grc3 (NFIA_034570)
Protein name
Polynucleotide 5'-hydroxyl-kinase grc3
Names
Species
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
KEGG Pathway
nfi:NFIA_034570
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-114 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1CYR9

Entry ID Method Resolution Chain Position Source
AF-A1CYR9-F1 Predicted AlphaFoldDB

No variants for A1CYR9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1CYR9

No associated diseases with A1CYR9

5 regional properties for A1CYR9

Type Name Position InterPro Accession
conserved_site MnmG-related, conserved site 270 - 284 IPR020595-1
conserved_site MnmG-related, conserved site 365 - 388 IPR020595-2
domain tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal 399 - 612 IPR026904
domain MnmG, N-terminal domain 6 - 394 IPR040131
domain tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain 542 - 613 IPR047001

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
polynucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKRKAEKQQA TAPVSAFAAR KARQQQAQLV EPEKTAQNEP AVEPPSKRAR WSPEEGAARQ
70 80 90 100 110 120
AANGNDRVQT RRSTRRKAET LSSELAEKQP QRSAAAARAQ IAERTPAPEK GDAETSDAAE
130 140 150 160 170 180
EEEEDILERE NGVGVIAAED DAEGYESPAD DVPQVQNFPL SKTRLNKSNI VFSDERTLCV
190 200 210 220 230 240
RIKEKMTLVL LGHYDLWVKR GVISLMGAKL HPSPRLYRVY APSTHSLPVI KCVAGVDGEA
250 260 270 280 290 300
EIEVKSCNSG IYRLRHLSPL YQRIWNGKNT AADKLTLKKA SASTKRTFSV LYTSSDDSWN
310 320 330 340 350 360
RHLRPLHLEK QWSSAIRSLS QRGGRLKVLI CGPKASGKST FSRYLLNHLL SPAPQTENNH
370 380 390 400 410 420
RNTDGVAFLD LDPGQPEFSP MGQVYLAHLR SPFFGPPFTH PSLAESQDGS IIRSHHIGVT
430 440 450 460 470 480
SPKEDPDHYV LAAMDLMDRY RALLASYPQC PLIINYPGWI FGLGLEVATW LVKSLGLSDV
490 500 510 520 530 540
VYMSEKGPAE VVEPLGHAAQ EARVPLTTLP SQPTDFVSRS SAQLRSMQVQ SYFHMSHPSE
550 560 570 580 590 600
IHNPQWLDTT MSRSRPLVVD YAGPRQGIRG IMVMGSQISP DLLHEALDGA LVGVVAVESP
610 620 630 640 650 660
NAIMGQADTA GFSGSSQRDA TQGAEDLSGA ASDVDMNDVT DASHGDVAPT SSSSVESMIT
670 680 690 700 710 720
RTPNEDLPYL FVGSGSCNPL DPKASNCLGL ALVRSIDVPS RKLELITPIP GSKLRDALEQ
730 740 750 760 770 780
GHGIVLVRGM LDNPSWAISE DYYAARAAEK HHQELVAKAR KETDTRDGRD AAGDADTQGM
790 800 810 820 830
VSALLRDRIR RASNVPWMTV IEDNSRRHRE AAQREKSLWK LRKKAYPGSE SETDW