A1CVQ6

PR
Gene name
NFIA_101920
Protein name
Mannitol 2-dehydrogenase
Names
M2DH, MDH
Species
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
KEGG Pathway
nfi:NFIA_101920
EC number
1.1.1.67: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1CVQ6

Entry ID Method Resolution Chain Position Source
AF-A1CVQ6-F1 Predicted AlphaFoldDB

No variants for A1CVQ6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1CVQ6

No associated diseases with A1CVQ6

2 regional properties for A1CVQ6

Type Name Position InterPro Accession
domain Mannitol dehydrogenase, C-terminal 232 - 474 IPR013118
domain Mannitol dehydrogenase, N-terminal 36 - 201 IPR013131

Functions

Description
EC Number 1.1.1.67 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
mannitol 2-dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPLKLNSKN LSQIAAAGGA LVKIPTYQRG RAVKEGIVHI GVGGFHRAHL AVYIDQLMQK
70 80 90 100 110 120
HGVTDYAICG VGLQPFDSAM RDALASQDHL YTLIERSAKG SFAHVIGSIN SYLFAPDNRE
130 140 150 160 170 180
AVIAKMAHPD TKIVSLTITE SGYYYNENTH ELQSEHPDIQ FDLDPANEKA PRTTFGFLYA
190 200 210 220 230 240
GLTRRYQQGL KPFTVMSCDN MQKNGSITRH MLESFARLRN PEVAEWIAEE GAFPNAMVDR
250 260 270 280 290 300
ITPQTSENDK TALADTFGIV DSWPVVTEPF TQWVIEDQFS NGRPPFEKVG VQVVKDVHAV
310 320 330 340 350 360
EQFEKHKLRL LNGSHSALGY PGQLAGFKYV HEVMENPLFR KFVWQMMQEE VKPLLPEIPG
370 380 390 400 410 420
VNIDEYCNTL IERFTNPTIM DQLPRICLNA SGKIPQFIMP SIAEAIWVTG PFRRLCFVAA
430 440 450 460 470 480
AWFHYVKGVD DSGKPFEVVD PMREELQAKA RAGGNDPFEL LSIKSLFGDD LRSDERFLKE
490 500
ITTAMNDIAR DGIMKTLPKY ID