A1CRK9
Gene name |
mcr1 (ACLA_030130) |
Protein name |
NADH-cytochrome b5 reductase 2 |
Names |
Mitochondrial cytochrome b reductase |
Species |
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) |
KEGG Pathway |
act:ACLA_030130 |
EC number |
1.6.2.2: With a heme protein as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1CRK9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1CRK9-F1 | Predicted | AlphaFoldDB |
No variants for A1CRK9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1CRK9 | |||||
No associated diseases with A1CRK9
8 regional properties for A1CRK9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Oxidoreductase FAD/NAD(P)-binding | 185 - 293 | IPR001433 |
| domain | Flavoprotein pyridine nucleotide cytochrome reductase | 125 - 132 | IPR001709-1 |
| domain | Flavoprotein pyridine nucleotide cytochrome reductase | 184 - 203 | IPR001709-2 |
| domain | Flavoprotein pyridine nucleotide cytochrome reductase | 210 - 219 | IPR001709-3 |
| domain | Flavoprotein pyridine nucleotide cytochrome reductase | 222 - 233 | IPR001709-4 |
| domain | Flavoprotein pyridine nucleotide cytochrome reductase | 279 - 287 | IPR001709-5 |
| domain | Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain | 77 - 172 | IPR008333 |
| domain | FAD-binding domain, ferredoxin reductase-type | 72 - 176 | IPR017927 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.6.2.2 | With a heme protein as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cytochrome-b5 reductase activity, acting on NAD(P)H | Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFARQPLRFA | QPLKQGFRKY | STEAPAKGKS | SLAPIYISVG | LAGLGVGLYR | YSTASAETPV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VDRPKVFTGG | EQGWVDLKLS | EIENLSHNTK | RLRFEFADKE | AVSGLQVASA | LLTKFKPAEG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KPVIRPYTPV | SDEDQPGYLD | LVVKVYPNGP | MSEHLHSMNV | DQRLEFKGPI | PKYPWETNKH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KHICLIAGGT | GITPMYQLAR | QIFKNPEDQT | KVTLVFGNVS | EEDILLKKEL | QELENTHPRR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FKAFYVLDNP | PKEWTGGKGY | VTKELLKTVL | PEPKEEDIKI | FVCGPPGMYK | AISGPKVSPK |
| 310 | 320 | ||||
| DQGELTGLLA | ELGYNKDQVY | KF |