Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A1CQI9

Entry ID Method Resolution Chain Position Source
AF-A1CQI9-F1 Predicted AlphaFoldDB

No variants for A1CQI9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1CQI9

No associated diseases with A1CQI9

4 regional properties for A1CQI9

Type Name Position InterPro Accession
domain K Homology domain, type 2 199 - 285 IPR004044
domain Small GTP-binding protein domain 9 - 166 IPR005225
domain GTP binding domain 12 - 126 IPR006073
domain Era-type guanine nucleotide-binding (G) domain 7 - 176 IPR030388

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Nucleus, nucleoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
PeBoW complex A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.
preribosome, large subunit precursor A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.

2 GO annotations of molecular function

Name Definition
large ribosomal subunit rRNA binding Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
ribonucleoprotein complex binding Binding to a complex of RNA and protein.

2 GO annotations of biological process

Name Definition
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNASKASKKR KAVTRDVEEE AGVFSGDELN ADNLDGALSD NANDLSSDED DSDSEIELVD
70 80 90 100 110 120
EFSEDDEDDE ELDSDEIPSD GEDAVKKKSV TTTDKSGEIA EDAESSSEEE ELDFRIEKDA
130 140 150 160 170 180
NGNDRFIYDE INPDDNSEYS DVEENSNTIG DIPLSFYDQY PHIGYDINGK KILRPAKGEA
190 200 210 220 230 240
LDALLDSIEI PKGWTGLTDP STGKPLELSQ DELELLRKVQ MNEIPEEGYN PYEPTVEWFT
250 260 270 280 290 300
SQQEIMPLSA APEPKRRFVP SKHEAKRVMK IVKAIREGRI LPFKPPTEED KEEDNVINYD
310 320 330 340 350 360
LWADEAERPD HIMHIPAPKL PPPGYEESYH PPPEYLPDKK ERKAWEEADP EDREQEFLPN
370 380 390 400 410 420
DFGSLRRVPG YENFVKEKFE RCLDLYLAPR VRRSKLNIDP ESLLPKLPSP EELKPFPTAC
430 440 450 460 470 480
ATVFRGHKGR VRSLAVDPSG LWLATAGDDG TVRVWELLTG RQLWSVKLSE EDPVNVVRWR
490 500 510 520 530 540
PGKDALILAA AAGDDIYLAV PPIVDPEVEK ASLDILDAGW GHAASVPALT PAEANKKNNP
550 560 570 580 590 600
PKWIRPSSSL QESGVCAIIP LRYIAKSLSW HRRGDYFVTV CPGSSTPASV AIAIHTLSKH
610 620 630 640 650 660
LTQYPFRRRI KGGGSPQAAH FHPSKPILFV ANQRSIRAYD LSRQLLVKIL QPGARWISSF
670 680 690 700 710 720
DIHPTSSTAS GGDNLIVGSY DRRLLWHDLE LSQRPYKTLR YHRKAIRAVK FHPGGRYPLF
730 740 750 760 770 780
ADASDDGSLQ IFHGSVTGDM LSNATIVPLK VLKGHKITGE LGVLDIDWHP REPWCVSAGA
DGTCRLWM