A1CLZ5

PR
Gene name
ACLA_078730
Protein name
Mannitol 2-dehydrogenase
Names
M2DH, MDH
Species
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)
KEGG Pathway
act:ACLA_078730
EC number
1.1.1.67: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1CLZ5

Entry ID Method Resolution Chain Position Source
AF-A1CLZ5-F1 Predicted AlphaFoldDB

No variants for A1CLZ5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1CLZ5

No associated diseases with A1CLZ5

2 regional properties for A1CLZ5

Type Name Position InterPro Accession
domain Geminivirus AL1 replication-associated protein, catalytic domain 7 - 119 IPR022690
domain Geminivirus AL1 replication-associated protein, central domain 126 - 229 IPR022692

Functions

Description
EC Number 1.1.1.67 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
mannitol 2-dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPLKLNSRN LSQIFAAGKS LVKVPTYQRN GAVKEGIVHI GVGGFHRAHL AVYVDRLMQE
70 80 90 100 110 120
QGVTDYAICG VGLQPFDSTM RDALASQDNL YTVIERSAKG SFAHVIGSIN SYLFAPDDRE
130 140 150 160 170 180
AVIAKMANPD TRIVSLTITE SGYYYNENTH ELQKEHPDIQ FDLNPVNENK PRTTFGFLYA
190 200 210 220 230 240
ALERRHRLGL KPFTVMSCDN MQKNGSITRH MLESFARQRN PKVAEWIAEE GAFPNAMVDR
250 260 270 280 290 300
ITPQTSATDK TALAENFGIE DSWPVVTEPF MQWVIEDKFS DGRPPFEKIG VQVVKDVHAV
310 320 330 340 350 360
EQFEKHKLRL LNGSHSAIGY PGQLAGFNYV HEVMEHPLFS KFVWQMMQQE VKPLLPEIPG
370 380 390 400 410 420
VNIDDYCNTL IERFTNPTIM DQLPRICLNA SGKIPQFIMP SIAEAIWVTA PFRRLCFVAA
430 440 450 460 470 480
AWFCYIKGID DSGKAFEVVD PMLNELQAKA RAGGTNPSEL LSIKNLFGDD LRTDPRFLKE
490 500
VTKAMEDITR DGILKTLPKY ID