A1CGA8

PR
Gene name
mndB (ACLA_066240)
Protein name
Beta-mannosidase B
Names
Mannanase B, Mannase B
Species
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)
KEGG Pathway
act:ACLA_066240
EC number
3.2.1.25: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1CGA8

Entry ID Method Resolution Chain Position Source
AF-A1CGA8-F1 Predicted AlphaFoldDB

No variants for A1CGA8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1CGA8

No associated diseases with A1CGA8

2 regional properties for A1CGA8

Type Name Position InterPro Accession
domain Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich 196 - 301 IPR006102
domain Mannosidase Ig/CBM-like domain 679 - 768 IPR041447

Functions

Description
EC Number 3.2.1.25 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
beta-mannosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.

1 GO annotations of biological process

Name Definition
polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAALQRFPLS KGWSFKDSED KSEDAWMPVP VVPSVVQQDL QANNKLKDPY IGFNELETRW
70 80 90 100 110 120
VNEKSWTYKT TFQKPAVPAG SAIFLAFDGL DTFATVKLDG NVILESDNMF LAHRLDVTKA
130 140 150 160 170 180
LEAEGDHSLE IDFDCAFLRA KELRKQDSKH NWASFNGDPS RLSVRKSQYH WGWDWGPVLM
190 200 210 220 230 240
TAGIWREVRL EVYTARVADL WTDVQLASDH QNAQITAFAE VESVNSDAHK ARFTLSLHGQ
250 260 270 280 290 300
ELGREEVSVS EDGSAKVSFD VKSPSLWWPH GYGDATLYEV SVSLVKDQDE VHQVSKKFGI
310 320 330 340 350 360
RTAEVVQQPD KHGKSFFFRV NGVDIFCGGS CWIPADNYLP SVTADRYRKW IELMVHGRQV
370 380 390 400 410 420
MIRVWGGGNY EDDSFYDACD ELGVLVWQDF MFGCGNYPTW PNLLESIRKE SVYNVRRLRH
430 440 450 460 470 480
HPSIVVWVGN NEDYQVQESA GLTYDFEDKN PENWLKTDFP ARYIYEKILP EVVEEYSPST
490 500 510 520 530 540
FYHPGSPWGD GKTTSDPTVG DMHQWNVWHG TQEKYQIFDT LGGRFNSEFG MEAFPHMSTI
550 560 570 580 590 600
DYFVENEADK FPQSHVLDFH NKADGHERRI ATYLVENLRT ATDLETHVYL TQVVQAETMM
610 620 630 640 650 660
FGYRGWRRQW GDERHCGGAL LWQLNDCWPT ISWAIVDYFL RPKPAFYAVA RVLNPIAVGV
670 680 690 700 710 720
RREHHDWSVT HAQPPKTSKF ELWVASSLQK EVQGTVELRF LSINTGLEVR ERIVHENVSI
730 740 750 760 770 780
VPNGTTNLIV DGLIDYKVHP EPHVLAVRIW VNGELVARDV DWPQPFKYLD LSNRGLEVKL
790 800 810 820 830 840
VSESENEQTL LLSAQKPVKC LVFEEREGVR ISDSAIDIVP GDEQRVTIKG MKPGDAPLKY
KFLGQ