A1CBE6
Gene name |
alg3 (ACLA_015020) |
Protein name |
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase |
Names |
Asparagine-linked glycosylation protein 6, Dol-P-Man-dependent alpha(1-3)-mannosyltransferase, Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase |
Species |
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) |
KEGG Pathway |
act:ACLA_015020 |
EC number |
2.4.1.258: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1CBE6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1CBE6-F1 | Predicted | AlphaFoldDB |
No variants for A1CBE6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1CBE6 | |||||
No associated diseases with A1CBE6
No regional properties for A1CBE6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A1CBE6 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.258 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity | Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| dolichol-linked oligosaccharide biosynthetic process | The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELNDFCIAT | IITALIILCE | TLSLLLHPGL | ELSRKRTNTI | GSLGLKPHAW | KPALWDLNTI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DNMELKHLLG | DLCMNPRHTR | WIAPLLILGD | AVLCALIIWR | VPYTEIDWTT | YMQQVSLYLS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GERDYTLIKG | STGPLVYPAA | HVYIYSILYY | LTDEGRDILL | AQILFAIPYL | ATLAVVMSCY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RQAGAPPFLL | LPLVLSKRLH | SIFVLRLFND | GFAALAMWIA | IFLFQKKKWT | AGVVVWSTGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AIKMTLLLLA | PAIAVVLVLS | LSLQPSIQLG | ALAVLIQILL | GIPFLSHNTA | GYIARSFELT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RQFMFKWTVN | WRFVGEELFL | SRKFSLALLA | LHIALLGLFA | TRVWLKPSGS | KLPSFVQQLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QRRYRTVSLS | RTFIMRTMLS | SLAIGLLCAR | SLHYQFFAYL | AWATPFLLWQ | TGFHPIVVYA |
| 430 | 440 | 450 | 460 | 470 | |
| VCMAQEWAWN | IYPSTNGSSL | VVILSLAVQV | IGILWNANGR | QIPENSPKEH | VQ |