A1C8R3

PR
Gene name
katG
Protein name
Catalase-peroxidase
Names
CP, Peroxidase/catalase
Species
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)
KEGG Pathway
act:ACLA_044200
EC number
1.11.1.21: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1C8R3

Entry ID Method Resolution Chain Position Source
AF-A1C8R3-F1 Predicted AlphaFoldDB

No variants for A1C8R3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1C8R3

No associated diseases with A1C8R3

4 regional properties for A1C8R3

Type Name Position InterPro Accession
domain Haem peroxidase 75 - 447 IPR002016-1
domain Haem peroxidase 418 - 724 IPR002016-2
binding_site Peroxidases heam-ligand binding site 275 - 285 IPR019793
active_site Peroxidase, active site 88 - 99 IPR019794

Functions

Description
EC Number 1.11.1.21 Peroxidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAESKCPFKS QGSRSNVAGG GTRNTDWWPE QLKLNILRQH TTVTNPLGAD FDYAAAFNTL
70 80 90 100 110 120
DYDALKKDLT ALMTDSQEWW PADFGHYGGL FIRMAWHSAG TYRVFDGRGG AGQGQQRFAP
130 140 150 160 170 180
LNSWPDNVSL DKARRLLWPI KQKYGDKISW ADLMILTGNV ALESMGFKTF GFAGGRADTW
190 200 210 220 230 240
EADESAYWGR ETTWLGNDAR YEKGFSGSDK QGTVIADEAS HKTTHSRELE NPLAAAHMGL
250 260 270 280 290 300
IYVNPEGPDG NPDPVAAAHD IRVTFGRMAM NDEETVALIA GGHTFGKTHG AAPADNVGKE
310 320 330 340 350 360
PEAAGLEAQG LGWQNSHGSG KGPDTITSGL EVTWTKTPTK WSNQFLEYLF KFDWELTKSP
370 380 390 400 410 420
AGAHQWVAKN ADDIIPDAYD AFKKHKPTML TTDLSLRFDP AYEKISRRFL ENPDQFADAF
430 440 450 460 470 480
ARAWFKLTHR DMGPRARYLG PEVPGEVLLW QDPIPAVNHA LIDTVDTAAL KRDVLATGVN
490 500 510 520 530 540
PSKFISTAWA AASTFRGSDK RGGANGARIR FAPQRSWEVN NQPWLQESLS ALEGVQSRFN
550 560 570 580 590 600
ASRPDRKQVS LADLIVLAGC AAVEQAAHDA GFPVRVPFTP GRMDASQDET DVESFSHMEP
610 620 630 640 650 660
IADGFRNYAK PYVHGRAEHY LVDKAQLLNL SAPEMTVLVG GLRVLNTNYD GSAHGVFTSR
670 680 690 700 710 720
PGVLSNDFFV NLLDMNTAWQ AGHNGEIFEG ADRKSGAKKW TATRADLVFG SHAELRAVAE
730 740 750
VYASADGQRK FVNDFVAAWN KVMNLDRFDL QGKQFIYPRL