A1BHN5

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Chlorobium phaeobacteroides (strain DSM 266)
KEGG Pathway
cph:Cpha266_1896
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

776-862 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1BHN5

Entry ID Method Resolution Chain Position Source
AF-A1BHN5-F1 Predicted AlphaFoldDB

No variants for A1BHN5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1BHN5

No associated diseases with A1BHN5

5 regional properties for A1BHN5

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 613 - 803 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 5 - 116 IPR007695
domain DNA mismatch repair protein MutS, core 272 - 595 IPR007696
domain DNA mismatch repair protein MutS, connector domain 125 - 256 IPR007860
domain DNA mismatch repair protein MutS, clamp 432 - 523 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSPPREHSP MMRQYLDVKE RYPDYLLLFR VGDFYETFFD DAKEVSSALN IVLTRRSNGS
70 80 90 100 110 120
SSEVPMAGFP HHASEGYIAR LVKKGYKVAV CDQVEDPSEA KGIVRREITD IVTPGITYSD
130 140 150 160 170 180
KILDDRHNNY LCALALLKEG RRVVAGAAFI DVTTAEFKIA ELLPEEVADF VRSLHPAELL
190 200 210 220 230 240
IARKEKERFE PVRKEFPPDM VVTELDDWMF GEDQASAVLA RQFKTHSLKG FGIHGNSAGK
250 260 270 280 290 300
VAAGVILQYL EETRQNRLHY ITRIGTLQNT DYMTLDLQTR RNLEIISSMQ DGTINGSLLQ
310 320 330 340 350 360
VIDRTANPMG ARLIRRWLQS PLKRLEDIAL RLDAVEEFKD FSPLRREVHG HLSEINDLER
370 380 390 400 410 420
VLSRIATFRS IPREMRQFGS ALSKIPLLKE ALLQTTTARL QALGRSLVEM PELVALIEKA
430 440 450 460 470 480
VDPEAGASMR DGGYIRAGYH QELDELRTIA STAKDRLLEI QQEERARTSI SSLKVQFNKV
490 500 510 520 530 540
FGYYIEISKS NLDKVPDYYE KKQTLVNAER FTIPALKEYE AKILNAEEKS IVLEQRLFHD
550 560 570 580 590 600
LSLLIAEQAA LVQTNAAVIA EIDCLASFAA VAEEYGYCKP EVAGHDRLLV TGGRHPVLER
610 620 630 640 650 660
MMSTDDPYVS NDLLFDRKQR LLIITGPNMA GKSSYLRQAG LIVLLAQAGS FVPAQKAEIG
670 680 690 700 710 720
LVDRIFTRVG ASDNLASGES TFLVEMNEAA SILNNATSKS LLLLDEIGRG TSTSDGMSIA
730 740 750 760 770 780
WSMSEFIHDS IGARTLFATH YHELAELETR LQGVVNYNAT VIETAEKVIF LRKIVRGASD
790 800 810 820 830 840
NSYGIEVARM AGMPQEVIVR AKEILAGMEK REIDVSGIKQ PSIESMQISL FEEADSRLRT
850 860 870
AIENLDLDRL TPLDALIELK KLQDLALKGC GR