A1BE50
Gene name |
macB |
Protein name |
Macrolide export ATP-binding/permease protein MacB |
Names |
|
Species |
Chlorobium phaeobacteroides (strain DSM 266) |
KEGG Pathway |
cph:Cpha266_0622 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1BE50
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1BE50-F1 | Predicted | AlphaFoldDB |
No variants for A1BE50
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1BE50 | |||||
No associated diseases with A1BE50
6 regional properties for A1BE50
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 5 - 242 | IPR003439 |
| domain | AAA+ ATPase domain | 33 - 219 | IPR003593 |
| domain | ABC3 transporter permease protein domain | 538 - 649 | IPR003838 |
| conserved_site | ABC transporter-like, conserved site | 144 - 158 | IPR017871 |
| domain | MacB, ATP-binding domain | 5 - 220 | IPR017911 |
| domain | MacB-like periplasmic core domain | 275 - 497 | IPR025857 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNPLLELLDV | HRTYQIGETT | VNALRGVSLT | IDRGEFVAIM | GASGSGKSSL | LQILGLLDNP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DKGEFKILGN | NVNTLSEDEQ | AGVRNNVAGF | VFQQFHLLKR | MTIVDNVRLP | HIYSGLKGDF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RQEAIARLKL | VGLEERIDHT | PNQLSGGEQQ | RVAIARALVR | DPLIIFADEP | TGNLDSKNSA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EIMKIFTALH | EEGKTIIMVT | HENDIAAYAC | RVIIMKDGLI | VSDERKAEMQ | PSRAVTGESA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FDISGSGKGS | IWQDGRFTGF | MAQAFQSILA | NKMRTFLSVL | GIFVGVASVI | AMMALGEGAK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SAMQEQLKSM | GSNMLSIRGG | SAKIRGAAQG | AGAVARFSFN | DVNDIASLGK | LVKNASGVVN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GSARIVYGNK | NWSSTLTGVG | FDYGTMRASI | PAIGRWFTRE | EIQIREKSAI | IGVTVVKEIF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GSSNPIGKTI | KINRINFKVI | GIAPAKGFSG | PQDEDDVVII | PVTTAMYRVL | GKDYLSSIFV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EVASPGLMGQ | AKTAITELIR | KKHRLEEGDD | SFNIRDMTEI | QKMLSSTTQT | MSLLLGSIAA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ISLLVGGIGI | MNIMLVSVTE | RTREIGLRKA | IGARKNDIML | QFLIESVGMT | ISGGLIGVFA |
| 610 | 620 | 630 | 640 | 650 | |
| GVGISLILAF | FAGWAVKTSL | LSVVLATTFS | ALIGVFFGLW | PARKAAALKP | VEALRYE |