Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A1AV99

Entry ID Method Resolution Chain Position Source
AF-A1AV99-F1 Predicted AlphaFoldDB

No variants for A1AV99

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1AV99

No associated diseases with A1AV99

5 regional properties for A1AV99

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 315 - 482 IPR000795
domain Small GTP-binding protein domain 318 - 474 IPR005225
domain Translation initiation factor IF-2, N-terminal 240 - 290 IPR006847
domain Translation initiation factor IF- 2, domain 3 590 - 705 IPR023115
domain Translation initiation factor IF-2, domain II 490 - 584 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAHTVQTLSK LLKKTPDEVI TILANAGVDG KNSDSAISAE ERKILMSSLS KRSSSKSSMF
70 80 90 100 110 120
SFSKTGIKSS ANSASGAKVQ VKKKRLTKSA TATDEQPEIA VNEVAQAVQV ALDAGRDADK
130 140 150 160 170 180
KLLAQDAKRL EMVRLQKTQA EVLKAQKKTV KQAQAQEIEK KAEKPKMIDK FKEDKKPKRL
190 200 210 220 230 240
RNTLNGNNTR RQLHVARHNP NRKLKKKDRT RLSQKVQEEQ AQHAFQKPIE KVVHEIAIAE
250 260 270 280 290 300
NIKVTELAQK MATKAGEVLK VLMGMGVMAT LNDVIDQDTA MLVVEEMGHK SIASVEETVE
310 320 330 340 350 360
DVLIEQLKSS GNEKARPPVV TIMGHVDHGK TSLLDYIRQA KVTHGEAGGI TQHIGAYQVQ
370 380 390 400 410 420
SNGNTITFID TPGHAAFSKM RSRSANATDI VILVVAADDG VMPQTIESIK HVQTAGVPMI
430 440 450 460 470 480
VAINKIDKEG IDIDKIKQVL STHNVISEDW GGDVMMIPVS AYTGEGVDAL LDAISLTAEV
490 500 510 520 530 540
LEFSAVIKAL ARGTVLEARL EKGRGKVTTI LVQSGTLNKG DIMIAGFEYG KVKQIVDDKG
550 560 570 580 590 600
KVLKSATPSM PVEVLGLSGV PNSGDEVLVV DSERKAREVA DFRKAKNREA QLQKQQASKM
610 620 630 640 650 660
ENFLMKMEES NVSTVNVLLK ADVRGSAQAL IEALEGLSTD EAKVKVVSSG VGGINNTDIT
670 680 690 700 710 720
LAATSNALVL GFNVRADAVA RKTADNEGVR IEYYSIIYNL IDDVKTIMSG LLSPELSENI
730 740 750 760 770 780
IGIASVKSVF RSQKMGDIAG CMVEEGVVRR DSLIRVLRDS VVIFEGWLES LRRFKDNVNE
790 800 810
VKSGTECGIG VLNYTDIQPG DQIEVFERIE RIRTL