A1A8H7
Gene name |
allB |
Protein name |
Allantoinase |
Names |
Allantoin-utilizing enzyme |
Species |
Escherichia coli O1:K1 / APEC |
KEGG Pathway |
ecv:APECO1_1503 |
EC number |
3.5.2.5: In cyclic amides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1A8H7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1A8H7-F1 | Predicted | AlphaFoldDB |
No variants for A1A8H7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1A8H7 | |||||
No associated diseases with A1A8H7
5 regional properties for A1A8H7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Creatinase, N-terminal | 49 - 183 | IPR000587 |
| domain | Peptidase M24 | 361 - 573 | IPR000994 |
| conserved_site | Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site | 519 - 531 | IPR001131 |
| domain | Peptidase M24, C-terminal domain | 594 - 656 | IPR032416 |
| domain | Aminopeptidase P | 361 - 591 | IPR033740 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.2.5 | In cyclic amides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| allantoinase activity | Catalysis of the reaction: allantoin + H2O = allantoate. |
| cobalt ion binding | Binding to a cobalt ion (Co). |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| allantoin catabolic process | The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. |
| purine nucleobase metabolic process | The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFDLIIKNG | TVILENEARV | VDIAVKDGKI | AAIGQDLGDA | KDVMDASGLV | VSPGMVDAHT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HISEPGRSHW | EGYETGTRAA | AKGGITTMIE | MPLNQLPATV | DRASIELKFD | AAKGKLTIDA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AQLGGLVSYN | IDRLHELDEV | GVVGFKCFVA | TCGDRGIDND | FRDVNDWQFF | KGAQKLGELG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QPVLVHCENA | LICDALGEEA | KREGRVTAHD | YVASRPVFTE | VEAIRRVLYL | AKVAGCRLHV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CHVSSPEGVE | EVTRARQEGQ | DVTCESCPHY | FVLDTDQFEE | IGTLAKCSPP | IRDLENQKGM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WEKLFNGEID | CLVSDHSPCP | PEMKAGNIMK | AWGGIAGLQS | CMDVMFDEAV | QKRGMSLPMF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GKLMATNAAD | IFGLQQKGRI | APGKDADFVF | IQPNSSYVLT | NDDLEYRHKV | SPYVGRTIGA |
| 430 | 440 | 450 | |||
| RITKTILRGD | VIYDIEQGFP | VAPKGQFILK | HQQ |