A1A4J8
Gene name |
SCO1 (SCOD1) |
Protein name |
Protein SCO1 homolog, mitochondrial |
Names |
|
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:508586 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1A4J8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1A4J8-F1 | Predicted | AlphaFoldDB |
39 variants for A1A4J8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs526976330 | 3 | G>E | No | EVA | |
| rs467718182 | 5 | L>S | No | EVA | |
| rs450581253 | 7 | A>E | No | EVA | |
| rs521912507 | 8 | P>R | No | EVA | |
| rs464865807 | 14 | L>I | No | EVA | |
| rs459269106 | 17 | S>R | No | EVA | |
| rs479171391 | 17 | S>R | No | EVA | |
| rs480961505 | 19 | L>H | No | EVA | |
| rs480961505 | 19 | L>P | No | EVA | |
| rs442453634 | 19 | L>V | No | EVA | |
| rs451785982 | 36 | T>P | No | EVA | |
| rs441333842 | 42 | G>E | No | EVA | |
| rs384503787 | 107 | A>T | No | EVA | |
| rs450428664 | 125 | E>G | No | EVA | |
| rs478547399 | 126 | K>E | No | EVA | |
| rs441083529 | 126 | K>R | No | EVA | |
| rs472529674 | 127 | L>M | No | EVA | |
| rs455503729 | 128 | E>G | No | EVA | |
| rs441829537 | 130 | E>G | No | EVA | |
| rs456249479 | 132 | H>Q | No | EVA | |
| rs476272280 | 132 | H>R | No | EVA | |
| rs432696594 | 133 | R>G | No | EVA | |
| rs464162672 | 134 | S>G | No | EVA | |
| rs453684108 | 136 | G>* | No | EVA | |
| rs434271076 | 139 | L>V | No | EVA | |
| rs468878430 | 145 | S>C | No | EVA | |
| rs483283875 | 147 | T>K | No | EVA | |
| rs448649831 | 147 | T>P | No | EVA | |
| rs446114237 | 156 | D>E | No | EVA | |
| rs477349916 | 159 | Y>F | No | EVA | |
| rs460375343 | 180 | E>K | No | EVA | |
| rs478940848 | 182 | E>Q | No | EVA | |
| rs475879411 | 199 | N>I | No | EVA | |
| rs449299402 | 221 | V>E | No | EVA | |
| rs458014259 | 230 | G>V | No | EVA | |
| rs438410348 | 232 | T>A | No | EVA | |
| rs723941016 | 236 | E>K | No | EVA | |
| rs480153902 | 240 | Q>E | No | EVA | |
| rs479272240 | 293 | S>* | No | EVA |
No associated diseases with A1A4J8
No regional properties for A1A4J8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A1A4J8 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of mitochondrial inner membrane | The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial cytochrome c oxidase assembly | The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O75880 | SCO1 | Protein SCO1 homolog, mitochondrial | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGLLLAPGR | IMRLPGSQLW | RLFPRGFGVW | GPGKETASVL | LGRLCARPEE | AWRASGLAAC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CLGSRPLSTA | MPPPPGSSGP | EWKGSGDPMR | PSKPGPVSWK | SLAVTFAIGG | ALLAGMKYFK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KEKTEKLEKE | RHRSIGKPLL | GGPFSLTTHT | GEPKTDKDYL | GQWVLIYFGF | THCPDICPEE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LEKMIQVVDE | IDSIPTLPNL | TPLFITIDPE | RDTKEAIANY | VKEFSPKLIG | LTGTKEEIDQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VARAFRVYYS | PGPKDEDEDY | IVDHTIIMYL | IGPDGEFLDY | FGQNKKNAEI | AGSIAAHMRT |
| HRKKS |