A0RQR9

PR
Gene name
hldE
Protein name
Bifunctional protein HldE
Names
Species
Campylobacter fetus subsp fetus (strain 82-40)
KEGG Pathway
cff:CFF8240_1413
EC number
2.7.1.167: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

54-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0RQR9

Entry ID Method Resolution Chain Position Source
AF-A0RQR9-F1 Predicted AlphaFoldDB

No variants for A0RQR9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0RQR9

No associated diseases with A0RQR9

2 regional properties for A0RQR9

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II 1 - 282 IPR006195
domain Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain 13 - 321 IPR041715

Functions

Description
EC Number 2.7.1.167 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
heptose 7-phosphate kinase activity Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.
heptose-1-phosphate adenylyltransferase activity Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.
phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).

1 GO annotations of biological process

Name Definition
ADP-L-glycero-beta-D-manno-heptose biosynthetic process The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVNVLVVGDL MIDHYVWGSC DRISPEAPVQ VVNIKNETKR LGGLGNVVSN LKTLGSEVGV
70 80 90 100 110 120
ISVVGDDDVG DEILELLKDR GAKTELIIKE KGRKSSQKSR IMVAHQQVLR LDTESVCEIG
130 140 150 160 170 180
VSDDIISKFE NILSGYDIVL LSDYGKGVLS PYLTKEIIRI TKKSGKMVLI DPKGKDYSKY
190 200 210 220 230 240
SGATLLTPNK KEASEALGFG INDEDDLKHA LKMLKDKFKL NYSLITLSED GIALLDEDVK
250 260 270 280 290 300
KFPALAKEVF DVTGAGDSVL ATLGYCLASK MSLEESIEIA NLAAAVVVGK VGSADASWGE
310 320 330 340 350 360
IENLKSKKSG FERKIISLDE LLRVDRSGKT MVFTNGCFDI LHFGHISYLQ SAKKIGDMLV
370 380 390 400 410 420
VGLNSDRSVK ELKGDNRPVN AQSDRASMLA ALEFVDFVVI FDEDTPLNLI KTLKPDILVK
430 440 450
GADYTGKKVV GSEFVREVKL IDFVDGKSTT NIINKIKG