A0RFA4
Gene name |
ssuB |
Protein name |
Aliphatic sulfonates import ATP-binding protein SsuB |
Names |
|
Species |
Bacillus thuringiensis (strain Al Hakam) |
KEGG Pathway |
btl:BALH_2614 |
EC number |
7.6.2.14: Linked to the hydrolysis of a nucleoside triphosphate |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A0RFA4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A0RFA4-F1 | Predicted | AlphaFoldDB |
No variants for A0RFA4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A0RFA4 | |||||
2 associated diseases with A0RFA4
[MIM: 601626]: Leukemia, acute myelogenous (AML)
A subtype of acute leukemia, a cancer of the white blood cells. AML is a malignant disease of bone marrow characterized by maturational arrest of hematopoietic precursors at an early stage of development. Clonal expansion of myeloid blasts occurs in bone marrow, blood, and other tissue. Myelogenous leukemias develop from changes in cells that normally produce neutrophils, basophils, eosinophils and monocytes. {ECO:0000269|PubMed:19184099}. Note=The gene represented in this entry may be involved in disease pathogenesis.
Without disease ID
- A subtype of acute leukemia, a cancer of the white blood cells. AML is a malignant disease of bone marrow characterized by maturational arrest of hematopoietic precursors at an early stage of development. Clonal expansion of myeloid blasts occurs in bone marrow, blood, and other tissue. Myelogenous leukemias develop from changes in cells that normally produce neutrophils, basophils, eosinophils and monocytes. {ECO:0000269|PubMed:19184099}. Note=The gene represented in this entry may be involved in disease pathogenesis.
Functions
| Description | ||
|---|---|---|
| EC Number | 7.6.2.14 | Linked to the hydrolysis of a nucleoside triphosphate |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTVLINEVSK | YFSKQTGTVQ | VLENINFQLE | KGDFVTVIGP | SGCGKSTLLK | IVAGLDNDFE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GEIIIDGERI | TKPSKKQGFI | FQEHRLFPWL | TVEENIAADL | SLKDKYVKDK | VKEWVEIVRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGFEKSYPKE | ISGGMSQRVA | IARALLRDPS | VLLLDEPFGA | LDAFTRSHLQ | EVLLNIWEQK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KTTMIFVTHD | IDEAIYLSNR | IVIMSAKPGK | IHKVIENNLP | YPRSKTSESF | QEIRKKVLQQ |
| 250 | |||||
| FEHGGLIQTS | I |