A0R4M9
Gene name |
otsA |
Protein name |
Trehalose-6-phosphate synthase |
Names |
TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA |
Species |
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) |
KEGG Pathway |
msm:MSMEG_5892 |
EC number |
2.4.1.15: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A0R4M9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A0R4M9-F1 | Predicted | AlphaFoldDB |
No variants for A0R4M9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A0R4M9 | |||||
No associated diseases with A0R4M9
No regional properties for A0R4M9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A0R4M9 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.15 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity | Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP. |
| alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity | Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| trehalose biosynthetic process | The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSPESGHETI | SGTSDFVVVA | NRLPVDLERL | PDGTTRWKRS | PGGLVTALEP | LLRKRRGSWI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GWAGVADSDE | EPIVQDGLQL | HPVRLSADDV | AKYYEGFSNA | TLWPLYHDLI | VKPEYHREWW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DRYVEVNRRF | AEATARAAAE | GATVWIQDYQ | LQLVPKMLRM | LRPDVTIGFF | LHIPFPPVEL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FMQMPWRTEI | VEGLLGADLV | GFHLPGGAQN | FLVLSRRLVG | ANTSRASIGV | RSRFGEVQVG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FRTVKVGAFP | ISIDSAELDG | KARNRAIRQR | ARQIRAELGN | PRKIMLGVDR | LDYTKGIDVR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LRALSELLEE | KRIKRDDTVL | VQLATPSRER | VESYIAMRED | IERQVGHING | EYGEVGHPIV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HYLHRPIPRD | ELIAFFVAAD | VMLVTPLRDG | MNLVAKEYVA | CRSDLGGALV | LSEFTGAAAE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LRQAYLVNPH | DLEGVKDKIE | AAVNQNPEEG | KRRMRALRRQ | VLAHDVDRWA | RSFLDALAAT |
| 490 | 500 | ||||
| GETGDSGVTG | ESTPAPESDS | GSF |