A0R3S7

PR
Gene name
ku
Protein name
Non-homologous end joining protein Ku
Names
Species
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
KEGG Pathway
msm:MSMEG_5580
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

194-318 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0R3S7

Entry ID Method Resolution Chain Position Source
AF-A0R3S7-F1 Predicted AlphaFoldDB

No variants for A0R3S7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0R3S7

No associated diseases with A0R3S7

1 regional properties for A0R3S7

Type Name Position InterPro Accession
domain Ku70/Ku80 beta-barrel domain 11 - 191 IPR006164

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
double-stranded DNA binding Binding to double-stranded DNA.

2 GO annotations of biological process

Name Definition
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
double-strand break repair via nonhomologous end joining The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRSIWKGSIA FGLVNVPVKV YSATEDHDIK FHQVHAKDNG RIRYKRVCEV CGEVVEYRDI
70 80 90 100 110 120
NKAFESDDGQ MVVITDEDIA TLPEERSREI EVVEFIPAEQ LDPLMYDKSY FLEPDSKSSK
130 140 150 160 170 180
SYVLLAKTLA ETDRIAIVHF SLRNKSRLAA LRVKDFSKRD VMMIHTLLWP DEIRDPDFPI
190 200 210 220 230 240
LDKEVQIKPA ELKMAGQVVE SMTDDFKPDL YHDDYQEQLR ELVQAKLEGG EAFSVEEQPA
250 260 270 280 290 300
ELDEGTEDVS DLLAKLEASV KARKGGKSDS KDDSDSESDS KESKSDSKPA KKAPAKKAAA
310
KKSTAKKAPA KKAAAKKS