A0R3Q8
Gene name |
rnhA |
Protein name |
Ribonuclease H |
Names |
RNase H |
Species |
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) |
KEGG Pathway |
msm:MSMEG_5562 |
EC number |
3.1.26.4: Endoribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A0R3Q8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A0R3Q8-F1 | Predicted | AlphaFoldDB |
No variants for A0R3Q8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A0R3Q8 | |||||
No associated diseases with A0R3Q8
1 regional properties for A0R3Q8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribonuclease HII/HIII domain | 70 - 253 | IPR024567 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.26.4 | Endoribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| nucleic acid binding | Binding to a nucleic acid. |
| RNA-DNA hybrid ribonuclease activity | Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSQDPVIIHT | DGGCRPNPGP | GGWGAVLRHR | EHVREMFGGE | AAVTSNNRME | LTAPIMALEA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LTRPVTVHLY | TDSTYVRNGI | TKWVLGWERN | GWMTAAKQPV | KNVDLWQRLQ | AACARHQVEW |
| 130 | 140 | 150 | |||
| FWVKGHSGIG | DNELADELAT | RGLQEAVGLT | TSSAGTSLR |