A0Q5D8

PR
Gene name
lptD
Protein name
LPS-assembly protein LptD
Names
Species
Francisella tularensis subsp novicida (strain U112)
KEGG Pathway
ftn:FTN_0558
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-142 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0Q5D8

Entry ID Method Resolution Chain Position Source
AF-A0Q5D8-F1 Predicted AlphaFoldDB

No variants for A0Q5D8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0Q5D8

No associated diseases with A0Q5D8

2 regional properties for A0Q5D8

Type Name Position InterPro Accession
domain Organic solvent tolerance-like, N-terminal 115 - 258 IPR005653
domain LptD, C-terminal 365 - 773 IPR007543

Functions

Description
EC Number
Subcellular Localization
  • Cell outer membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cell outer membrane A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
Gram-negative-bacterium-type cell outer membrane assembly The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.
lipopolysaccharide transport The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
response to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKGIHKYLL MCFGTVLFTV QANAARIMSN NPIKEDWQCK VVDGEWSCKR AKKPKSVFDK
70 80 90 100 110 120
KLTKTEKEKA LADDLAWVKK PSYFVGGYYS NDSQFTKALC ESKKTDLSYE KSEFDNDGTL
130 140 150 160 170 180
IASGNVQVLQ CDQELYGNNA IINLNSNNSA IRSLVMAGDV IVKQPSTGIV IRTTELDADM
190 200 210 220 230 240
NDGTYSTGEA YFRLAREMPK TRIYDKEHFS GYLRGYAKTF KKESSGDIVL SDGYITSGDP
250 260 270 280 290 300
YDNAWKITGN NIDIDTNTHM AYVKNGYFEI QDIPVMYIPY FSHPIDDRRR SGFLYPGFVQ
310 320 330 340 350 360
NANSGIGISV PYYFNLAPNY DLMLQSVIWS QRGIMENGTF RYMTKYFQGQ FEGSLVPYDF
370 380 390 400 410 420
KEGKMRGSFT LSTTGQYENI NTNFKYEYVS DQNYYNDFSA GNVNLVTKTL LDREFDLTYT
430 440 450 460 470 480
NDYVDSGLTV LDYGVVNPLL TVDNTPYAKL PEVKLNLTSD GYTPDYLTLS AQTLNTFFYK
490 500 510 520 530 540
TAGPANTNPG APQGTNVNAF RAYESPKIAF NFNKTWGYLN PSLEVPIRYY QLKNSPTDTI
550 560 570 580 590 600
QFANSSVTSV LPIFNIDAGA YFDKDYTNEN GTYTSTLHPR LFYTYIPYQD QTNIPLFDTS
610 620 630 640 650 660
LQNEQYMQMF QVNRFTGYDR INNANQLTYA LEASTTNQED GTTLASAKIG QMAYFADRKV
670 680 690 700 710 720
NLCQGNSACP NPGLMDPFST DTFSPIMTSF EFQVMKNIYL SAQVNYRVKQ QNVDYQVYQL
730 740 750 760 770 780
SYKDENENIF NVSYNNIANN WSSLTQQQIA EGAKPQPQET ITLSTILNIT DHWGIAALWN
790 800 810 820 830 840
YNFQQKQIAN IFAGLQYNAK SWAVRALWQK TAYTNQDPNN PTLLGPLVNT YMFEFELKGL
850 860
GGIGNTSDIS SRLQQINGYQ VGEWGDGI