A0LYR8

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Gramella forsetii (strain KT0803)
KEGG Pathway
gfo:GFO_0530
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

997-1108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0LYR8

Entry ID Method Resolution Chain Position Source
AF-A0LYR8-F1 Predicted AlphaFoldDB

No variants for A0LYR8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0LYR8

No associated diseases with A0LYR8

8 regional properties for A0LYR8

Type Name Position InterPro Accession
domain Helicase, C-terminal 602 - 786 IPR001650
domain SecA DEAD-like, N-terminal 8 - 582 IPR011115
domain SecA Wing/Scaffold 769 - 1017 IPR011116
domain SecA, preprotein cross-linking domain 398 - 538 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 179 - 338 IPR014001
domain SecA motor DEAD 5 - 770 IPR014018
conserved_site SecA conserved site 680 - 695 IPR020937
domain SecA, C-terminal helicase domain 600 - 740 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFLDSVLKA FVGDKSKKDV KEIQPIVNKI KALESEFEAL SLDELRAKTS EFKAKIAEAT
70 80 90 100 110 120
KEVEDKIVAL NKEADEIDDI TRKEDIYAEV DALKEKSYEI SEAVLNDILP EAFATVKETA
130 140 150 160 170 180
KRFVNNTQLK VKASSFDREI SAEKDYVTLE DDHAIWSNSW DAAGKPVTWD MVHYDVQLIG
190 200 210 220 230 240
GVAMHQGKIA EMQTGEGKTL VATLPMYLNA LTGNGVHLVT VNDYLAKRDS AWMAPIFQFH
250 260 270 280 290 300
GMSVDCVDYH RPNSAARRKA YNADITYGTN NEFGFDYLRD NMSHAPDDLV QRPHNYAIVD
310 320 330 340 350 360
EVDSVLVDDA RTPLIISGPV PKGDTHEFME LKPAIANIVE VQRKHLVKVL SEAKKLIKEG
370 380 390 400 410 420
DTKEGGFQLL RVYRGLPKNK ALIKFLSEEG IKQLLQKTEN HYMQDNNREM PKVDAELYFT
430 440 450 460 470 480
IEEKSNQIDL TDKGIEFLSG KDEPDFFVMP EIGMEIAKIE KEGFPAEEEA EKKEELFRDY
490 500 510 520 530 540
SVKSERIHTL RQLLKSYTLF EKDTEYVVID NKVKIVDEQT GRIMEGRRYS DGLHQAIEAK
550 560 570 580 590 600
ENVKIEDATQ TFATVTLQNY FRMYGKLSGM TGTAVTEAGE LWEIYKLDVV EIPTNRPIAR
610 620 630 640 650 660
NDKEDLVYKT KREKYNAVID HVTDLSNAGR PVLIGTTSVE ISELLSRMLK LRNVPHNVLN
670 680 690 700 710 720
AKRHKQEADI VAEAGNSGIV TIATNMAGRG TDIKLSKEVK EAGGLAIVGT ERHDSRRVDR
730 740 750 760 770 780
QLRGRAGRQG DPGSSQFYVS LEDNLMRLFG SERIAKLMDR MGLEEGEVIQ HSMISKSIER
790 800 810 820 830 840
AQKKVEENNF GVRKRLLEYD DVMNAQREVI YKRRYHALFG ERLRVDLANM IFDISESITE
850 860 870 880 890 900
TNKAAEDFKN FEFELIRNFS MSSPVSEEEF KKMNAQKLAG EVYKSAYKHY DEKMSHNAER
910 920 930 940 950 960
AFPVIKQVHE DERNNFERIS VPFTDGTKTL SVVTNLEKAY ETEGKQLIKD FEKNITLAII
970 980 990 1000 1010 1020
DDAWKTHLRK MDELKQSVQL AVHEQKDPLL IYKFEAFELF KVMLENVNRD VMSFLFKGEI
1030 1040 1050 1060 1070 1080
PSTGAPSIHE ARQTKSKEKV ETRKEEIPNM DERAAQSRAA GNTQRQQPEV TETIVRDRPK
1090 1100 1110
IGRNDKVTVK NVMSGESKTM KFKQAIPLLD KGDWVLVEE