A0LVS1

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B)
KEGG Pathway
ace:Acel_1759
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

811-1009 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0LVS1

Entry ID Method Resolution Chain Position Source
AF-A0LVS1-F1 Predicted AlphaFoldDB

No variants for A0LVS1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0LVS1

No associated diseases with A0LVS1

9 regional properties for A0LVS1

Type Name Position InterPro Accession
domain Helicase, C-terminal 415 - 624 IPR001650
conserved_site SEC-C motif 986 - 1003 IPR004027
domain SecA DEAD-like, N-terminal 5 - 387 IPR011115
domain SecA Wing/Scaffold 617 - 837 IPR011116
domain SecA, preprotein cross-linking domain 227 - 343 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 88 - 245 IPR014001
domain SecA motor DEAD 2 - 619 IPR014018
conserved_site SecA conserved site 485 - 500 IPR020937
domain SecA, C-terminal helicase domain 405 - 589 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPALLDKLLR AGEGKILRKL KAIAEQVNSI EDEFAKLSDG ELRGLTDEFR ARYADGESLD
70 80 90 100 110 120
DLLPEAFAAV REAAKRTLGQ RHFDVQIMGG AALHFGNIAE MKTGEGKTLV STLPAYLNAL
130 140 150 160 170 180
AGRGVHVVTV NDYLARRDAE WMGRIHRFLG LEVGVISPQM GPAERKKAYA ADITYGTNNE
190 200 210 220 230 240
FGFDYLRDNM AWSVDEIVQR GHFYAIVDEV DSILIDEART PLIISGPVDM NQKWYTDFAK
250 260 270 280 290 300
LAERLQRGEN GEGDYEVDEK KRTISITERG VQRVEDWLGI DNLYEPTNTP LVGYLHNALR
310 320 330 340 350 360
AKELYKRDRD YVVIDGEVLI VDEFTGRILY GRRYNEGMHQ AIEAKEGVPI KQENQTLATI
370 380 390 400 410 420
TLQNYFRLYE KLAGMTGTAM TEANEFHQIY KLGVVPIPTN RPMIRIDQPD VVFKTEKAKF
430 440 450 460 470 480
AAVVEDIAQR HAKGQPVLVG TTSVEKSELL SGMLLRRGIP HAVLNAKYHE KEAAIVAQAG
490 500 510 520 530 540
RKGAVTVATN MAGRGTDIML GGNPEFLARQ ELAERGLSPV DTPEEYEAAW PEVLEKWKKA
550 560 570 580 590 600
VAAEHDEVVQ LGGLYVLGTE RHDSRRIDNQ LRGRSGRQGD PGESRFYLSL EDDLMRLFNG
610 620 630 640 650 660
PMVQRIMETL NYPEDVPLES KMVTRAIRSA QTQVEQQNFE IRKNVLKYDE VLNKQRAVIY
670 680 690 700 710 720
AERRRVLHGD DLHEQVGHMI DDVIRDYVRA ATEEGYAEDW DLEQLWTALR SLYPVGLTID
730 740 750 760 770 780
QVVAECGGDR SGLTAEFLIE RLTEDAHRAY AEREAALGTL PDGQPVIREL ERRVVLAVLD
790 800 810 820 830 840
RKWREHLYEM DYLQEGIQLR SYGQRDPLVE YQREGYTMFQ TMLDGIKEES VRLLFSVDVQ
850 860 870 880 890 900
VTPVAEAPVA ATAAADGAGT AAEGTAGVAV PQPAGASGPA LQPVPAATAP GQQPVPAAAA
910 920 930 940 950 960
LSPGAGMRLA DSPVAKLLAP PRPTRLQYTA PTIDGAAGSG EATAMTVDER RPSGAAARGP
970 980 990 1000
SPASASRQRA GAGEQARPLM YAGTPRSAKC PCGSGKPYKR CHGDPRNAG