A0LJM5

PR
Gene name
nuoBCD (nuoB, nuoC, nuoD, Sfum_1942)
Protein name
NADH-quinone oxidoreductase subunit B/C/D
Names
NADH dehydrogenase I subunit B/C/D, NDH-1 subunit B/C/D
Species
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
KEGG Pathway
sfu:Sfum_1942
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

110-274 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0LJM5

Entry ID Method Resolution Chain Position Source
AF-A0LJM5-F1 Predicted AlphaFoldDB

No variants for A0LJM5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0LJM5

No associated diseases with A0LJM5

5 regional properties for A0LJM5

Type Name Position InterPro Accession
domain NADH-quinone oxidoreductase, subunit D 517 - 787 IPR001135
domain NADH:ubiquinone oxidoreductase, 30kDa subunit 248 - 373 IPR001268
domain NADH:ubiquinone oxidoreductase-like, 20kDa subunit 56 - 137 IPR006137
conserved_site NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site 440 - 451 IPR014029
conserved_site NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site 334 - 355 IPR020396

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

5 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
iron ion binding Binding to an iron (Fe) ion.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
NADH dehydrogenase (ubiquinone) activity Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
quinone binding Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDRFLSAAD FVLNWSRKYS LWPLFFGLSC CFVEEATAFT PRYDMARFGA EVLRPSPRQA
70 80 90 100 110 120
DLLIVSGTVF KKIAPVVLRL YEQMAEPKWV ISMGSCSNCG GMYDVYSVVQ GIDQILPVDV
130 140 150 160 170 180
YIPGCPPRPE AVLQGLTLLQ KKIAAEERPA RSVLHLPGGS QGSTRPVLVD GATKSRDPRG
190 200 210 220 230 240
PGMEGTVIRG TANTPPAFTG SRSDLMWTPP ARRIESSERE KELARVLSER FGDAVREEPF
250 260 270 280 290 300
TSDMPTFHVE TNRLKDVLGF LKKEASPRFL RLDDLTAVDE SARRDRSAYP DWTMVYHLLS
310 320 330 340 350 360
FEPAGRVRLK TGLHGRQPAL PSITDIWPSA NWYEREVYDL FGIRFEGHPN LRRIMMPHDW
370 380 390 400 410 420
EGHPLRKDYP GRATQMAPYT LGDARVHQPP DGGIFTKDPG GDRLVLNIGP SHVSTHGLLR
430 440 450 460 470 480
YVVSLDGEEI SDLELEIGYH HRGVEKIGER QTWHQFIPYC ARVDYLAGAA NDLPYVMAVE
490 500 510 520 530 540
TLADIKVPER AQVIRVLLSE LFRLSNHLVW FATYAHDVGA MTPNFYTFTE REMILDIVEL
550 560 570 580 590 600
ITGGRLHPSW FRLGGVAADL PEGWKEAVDA LVRIFPGRLR EYESLIRKNP IFKARTQGVG
610 620 630 640 650 660
RISREDAVDW GVSGPNLRAC GLEWDLRRKF PYSGYENFEF EVPTAVEGDC YARYLVRVEE
670 680 690 700 710 720
MRQSLRIIEQ AAANMPSGRH VTDDYRYVIP DRRDTLKNIE SLIHHFVNVT RGPRIPKGEA
730 740 750 760 770 780
YVSCEIPRGE QGYYVVGDGL GYAYRMRIRG PGFANVQVMP LLARGESIAD LIAIIGSVDY
ILPDIDR