A0LHL8

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
KEGG Pathway
sfu:Sfum_1228
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

9-404 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0LHL8

Entry ID Method Resolution Chain Position Source
AF-A0LHL8-F1 Predicted AlphaFoldDB

No variants for A0LHL8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0LHL8

No associated diseases with A0LHL8

6 regional properties for A0LHL8

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 455 - 624 IPR000795
domain Small GTP-binding protein domain 458 - 614 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 50 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 382 - 431 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 730 - 845 IPR023115
domain Translation initiation factor IF-2, domain II 630 - 723 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRMRVHELA KELNMDNKDL IDRILKLGIQ VKNHMSTLTD SAVLKIRQQF SEAKTETVEE
70 80 90 100 110 120
KRIGRAVIRR RKKLTEGESA AAPAEGEERV ASEALPVEAE MPAQPVEAPE LIAEPISKLP
130 140 150 160 170 180
PEVGVAQPQL PEEPEPAPEP LIPAVKPEEA AASELAVEPQ TVVPPVAAPA AEVKPARPPM
190 200 210 220 230 240
EAPAPARKPP EEKETKVKHA EPESLAEPLP SPAPVELTLV PAESAAGQVA ERTDEEEEED
250 260 270 280 290 300
DKARPKKAKK RRRKKVRKDE PARIIKLPEI IPEEPEEEAV LPAHLATRIQ VKTEEVEVKE
310 320 330 340 350 360
APRKKRPRPE EFEKEAAERK AKGTRRKEVF EREDLYSKQE IAAQDDRGRL KGDKRRPFAK
370 380 390 400 410 420
EPARPEIAVV KPGKRKIRVD EAITVANLAK QMGIKATELI KKLLLLGLPA NINQAVDFDT
430 440 450 460 470 480
AALLASEFEF EVEKTGFEEE ELLQVREDRV EDLIRRPPVI TVMGHVDHGK TSLLDAIRDT
490 500 510 520 530 540
NVIGGEAGGI TQHIGAYYVM LPNGNVVFLD TPGHEAFTSM RARGAKVTDI VILVVAADDG
550 560 570 580 590 600
VMQQTIEAIN HAKAAEVPII VAINKVDKPN ANIDRVKREL AEHGLIPEEW GGNVTMVGIS
610 620 630 640 650 660
AKKRTGIEEL LEMVLLQAEL LELKANPAKP ARGRVIEAKL DKGRGPVATI LIQEGTLRTG
670 680 690 700 710 720
DVYLCGVNSG RVRNMFSDRG QRLDEAGPSM PVEVLGLSGV PNAGDDFITL PDERQAKMIA
730 740 750 760 770 780
EHRLVKLREK ELSRTSKVTL ESLFEQIQEG EIKELNLILK ADVHGSLEAI TDSLLKLSTP
790 800 810 820 830 840
EVKVSLIHFG TGAVIETDVM LASASNAIVI GFNVRSETKV QELADQENVD VRYYDVIYQL
850 860 870 880 890 900
LSDVKDAMVG MLEPVFKENV IGRAEVRQTF QVPKIGMIAG SFVLEGRVER NAKCRVLRDH
910 920 930 940 950 960
VVTYDGKISS LRRFKDDAKE VKAGFECGIG VENFNDIKVG DILEVYELQE MKPVLESPPG
DK