Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A0KTZ6

Entry ID Method Resolution Chain Position Source
AF-A0KTZ6-F1 Predicted AlphaFoldDB

No variants for A0KTZ6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0KTZ6

No associated diseases with A0KTZ6

7 regional properties for A0KTZ6

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 389 - 558 IPR000795
domain Small GTP-binding protein domain 393 - 545 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 50 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 312 - 362 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 59 - 97 IPR013575
domain Translation initiation factor IF- 2, domain 3 665 - 779 IPR023115
domain Translation initiation factor IF-2, domain II 565 - 658 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADTTVEKLA TEVGKSVERL IEQFSQAGIK KGQTDNVSEA EKQQLLDYLK KQHGGESAPT
70 80 90 100 110 120
KMTLQRKTVS TLSVAGNGGQ SKDVKVEVRK TRTFVKRDVS EAVLKAEEEA KAKAEAEAQA
130 140 150 160 170 180
KAEAEAKARA EAEAKAKADA EAKAEAKAKA DAEAKAKAKA ATDAKTTKDT SPEAEAARVE
190 200 210 220 230 240
AERLKAAQAE ATKRKQDEEA AKAAEKARLL AEENSKRWDE EERQRKEAER YSDHHITTSK
250 260 270 280 290 300
VARAAEDSSD MDEEKRGRRA RNKNTAKTKR GGKDARDGRE KHMRNRSTAP ESMAHGFNKP
310 320 330 340 350 360
VAAVTRDVRI GETVTVAELA HLMAVKATEI IKQMMKMGSM VTINQVLDQE TAQLVAEEMG
370 380 390 400 410 420
HKVVLIRENE LEQQVLSERD EEGGVKLEPR APVVTIMGHV DHGKTSLLDY IRRAKVAAGE
430 440 450 460 470 480
AGGITQHIGA YHVETENGMI TFLDTPGHAA FTAMRARGAK ATDIVVLVVA ADDGVMPQTI
490 500 510 520 530 540
EAIQHAKAGN VPLIVAVNKM DKPEADIDRV KSELAQHGVM SEDWGGDNMF AFVSAKTGAG
550 560 570 580 590 600
VDDLLEGILL QAEVLELKAV RDGMAAGVVI ESQLDKGRGP VATILVQEGT LRQGDIVLCG
610 620 630 640 650 660
LEYGKIRAMK DENGRSITEA GPSIPVEILG LSGVPSAGDE ATVVRDERKA REVALYRQGK
670 680 690 700 710 720
FRDVKLARQQ KSKLENMFAN MTEGEVKELN IVLKADVQGS LEAITDSLMG LSTDEVKVNI
730 740 750 760 770 780
IARGVGALTE TDATLAAASN AIMVGFNVRA DAQARKTIES ESVDLRYYSV IYNLIDEVKA
790 800 810 820 830 840
AMTGMLSPEF KQQIIGLAEV RDVFKSPKLG AIAGCMVTEG TIKRSAPIRV LRDNVVIFEG
850 860 870 880
ELESLRRFKD DVNEVRNGME CGIGVKNYND VRVGDQIEVF ETVEVARTL