A0KKK7

PR
Gene name
rlmL
Protein name
Ribosomal RNA large subunit methyltransferase K/L
Names
Species
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)
KEGG Pathway
aha:AHA_2285
EC number
2.1.1.173: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

267-339 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0KKK7

Entry ID Method Resolution Chain Position Source
AF-A0KKK7-F1 Predicted AlphaFoldDB

No variants for A0KKK7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0KKK7

No associated diseases with A0KKK7

4 regional properties for A0KKK7

Type Name Position InterPro Accession
domain Ribosomal RNA large subunit methyltransferase K/L-like, FLD domain 162 - 375 IPR000241
conserved_site DNA methylase, N-6 adenine-specific, conserved site 306 - 312 IPR002052
domain THUMP domain 23 - 154 IPR004114
domain S-adenosylmethionine-dependent methyltransferase 453 - 664 IPR019614

Functions

Description
EC Number 2.1.1.173 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
23S rRNA (guanine(2445)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKEFFATCPK GLENLLAVEL TNLGAEQVRE TVAGVHFKGE LAIGYKACLW SRFASRIVLV
70 80 90 100 110 120
LSEFQMNDDL DLYLGAHTIP WEEHFSGTST IAVDFTGTNP AIRNTQYGAL KIKDAIVDRF
130 140 150 160 170 180
TKRGHVRPDV DKKSPDIRIM AHLGKGKANI TLDLSGPALH QRFYRQGTGE APLKENLAAA
190 200 210 220 230 240
MIARSGWAGE PMMDPMCGSG TLLVEAAFIA ADMAPALRRE RFGFDRWLQH DSELWQSLLM
250 260 270 280 290 300
EAQVRAKRGM QRCEVKLFGC DADSRVLLKA RDNAKAAGVA HLITFKQADV TALENPLPMP
310 320 330 340 350 360
APVEGEEGQG EARQVGMLIS NPPYGERLGE FPALLEVHQA LGDALRRSFQ GWKVSILSAS
370 380 390 400 410 420
PELLSCLRLR ADKQYRLFNG ALECQLRNYQ IAQDSVASQK EVAQDFANRL RKNLKTLEKW
430 440 450 460 470 480
AQKENLDCYR LYDADLPEYN AAIDRYQDYL VVQEYAAPKD IPAQKTRQRL LDMVQAAIKV
490 500 510 520 530 540
TGMDGEKVIL KVRERQEGKQ QYQKLSEEQH RMEVQEYGAR LWVNLYDYLD TGLFLDHRQT
550 560 570 580 590 600
RRMLGQMAKG KRFLNLFAYT GSATVHAGLG GASETTTVDM SRTYLNWAQD NMRLNSLVGR
610 620 630 640 650 660
EHKFVQADCL KWLSEADDQY DLIFIDPPTF SNSKRMDESF DVQRDHLLLM QHLKRLLAAG
670 680 690 700 710
GTLVFSNNKR HFKMDLAGLE AIGLKAQNIT GKTRPKDFER NQHIHNCWII THAEAQA