A0KGK4
Gene name |
mdtH |
Protein name |
Multidrug resistance protein MdtH |
Names |
|
Species |
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) |
KEGG Pathway |
aha:AHA_0853 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A0KGK4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A0KGK4-F1 | Predicted | AlphaFoldDB |
No variants for A0KGK4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A0KGK4 | |||||
No associated diseases with A0KGK4
1 regional properties for A0KGK4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 2 - 390 | IPR020846 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVERARRLGR | WFLALDSLLV | ILGFFVVMPM | ISLRFVDQLG | WAAGVVGLAL | GLRQLTQQGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GILGGSLADK | FGARPLIVGG | MLLRAAGFAS | LAYAQSGLEL | ILSCVISGLG | GCLFDPPRAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LVIKFTRPRQ | RGRYISLLMM | LESAGAVVGA | LLGSWLLNFD | FEYVCLLGAG | LFVCAALCNL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LILPAYKLSV | RPTPIRAGLG | QVLADKAFCR | LVLILSGYYA | LWVQVMLIFP | ILVKQMAGTT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TAVGWMYTLE | TAISLALLYP | LARYGERHFK | LESRLMAGVL | LMTTGIGLVA | FANTLPAVFM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLACFYLGIV | IAEPARETLM | TKLAQPGARG | SYMGFSRLGL | ALGGMTGYVG | GGALHDYAML |
| 370 | 380 | 390 | |||
| QGQPWLPWLV | LGTVGVTTLL | LLVNCFHREP | SLARVNI |