A0KFR1
Gene name |
rnb |
Protein name |
Exoribonuclease 2 |
Names |
Exoribonuclease II, RNase II, Ribonuclease II |
Species |
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) |
KEGG Pathway |
aha:AHA_0554 |
EC number |
3.1.13.1: Exoribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A0KFR1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A0KFR1-F1 | Predicted | AlphaFoldDB |
No variants for A0KFR1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A0KFR1 | |||||
No associated diseases with A0KFR1
5 regional properties for A0KFR1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribonuclease II/R | 191 - 517 | IPR001900 |
| domain | Cold shock domain | 23 - 79 | IPR011129 |
| domain | Ribonuclease B, N-terminal OB domain | 24 - 74 | IPR013223 |
| conserved_site | Ribonuclease II/R, conserved site | 484 - 508 | IPR022966 |
| domain | RNase II/RNase R, cold shock domain | 99 - 171 | IPR040476 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.13.1 | Exoribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| exoribonuclease II activity | Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFQDNPLLAQ | LKQQIRENIP | KKEGVIRASD | RGFGFLEVDE | KTSYFVPPPY | MKKVMHGDRV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SALIRTEKEK | EVAEPDALLE | QSVTRFVARV | KMFRDRLNVV | ADHPLIKDAI | KARVKKGLDE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KEFKEGDWVV | ATLKRHALVD | GNFSAEITQT | IASQEDHNVP | WWVVLARHNL | AQVEPADLPE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WKVIEEEELP | RTDLTATPFF | TIDGAKTKDM | DDALAIRKLD | NGWELLVAIA | DPTAYVAEGS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ELDKEAAQRA | FTVYMPGRNV | PMIPRTLSDE | LCSLKEGEER | NTLCARLLIA | EDGLLLEETE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FFAARISSHA | RLTYDDVSDW | AEHGKQLDID | AGVLAQLPLM | KAMTEARIAW | RTEHALVFPD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RPDYDFELGE | NGEVLAIHVE | PRRIANRMVE | ESMIAANICA | GRVLGKQVGY | GIFNVHTGFD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EESLDGAIDL | LKSAEAPFEK | EEIASLSGFC | ALRRWIDNLD | TRWLDGKIRR | FQSYALMSAE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PGAHYGLGLD | AYATWTSPIR | KYGDMVNHRL | LKAVIAGKTP | GERPSLELTE | HLTACRRLHR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| MVERDIGDWL | YVRYLKADAG | TDKVFNAEII | DVMRAGLKLR | LRENGAVVFM | PARHILDNKD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RLECNWDNGR | VYLDKTEVVY | ELGQIIEVKL | TEAVEETRSL | IAKPAVELVP | GPAPVAPTSE |
| 670 | |||||
| ADATPADEAP | KAE |