A0KEF8

PR
Gene name
ubiB
Protein name
Probable protein kinase UbiB
Names
Ubiquinone biosynthesis protein UbiB
Species
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)
KEGG Pathway
aha:AHA_0086
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

89-167 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0KEF8

Entry ID Method Resolution Chain Position Source
AF-A0KEF8-F1 Predicted AlphaFoldDB

No variants for A0KEF8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0KEF8

No associated diseases with A0KEF8

3 regional properties for A0KEF8

Type Name Position InterPro Accession
domain AMP-dependent synthetase/ligase domain 90 - 497 IPR000873
conserved_site AMP-binding, conserved site 229 - 240 IPR020845
domain AMP-binding enzyme, C-terminal domain 506 - 581 IPR025110

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.

3 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
regulation of ubiquinone biosynthetic process Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTPKEFKRLY RIISILLEQG IDELVPARYQ PWPGRLARRS LFWLKNKRQG LNRGARIRLA
70 80 90 100 110 120
FEALGPIFIK FGQMLSTRRD LLPPDIAEEL ALLQDRVPPF CGQAARRQIE ASLGCTIETL
130 140 150 160 170 180
FDDFDETPLA SASIAQVHTA RLKENGREIV IKVIRPDIEP VIEADLRLMQ ALARLVARFV
190 200 210 220 230 240
PQSGRLRPIE VVEEYRKTIL DELNLMREAA NAIQLRRNFT GSEALYVPEV FTEHCREQVL
250 260 270 280 290 300
VMERIYGIPV SDIAALEANG TNMKLLAERG VEVFFTQVFR DSFFHADMHP GNIFVSYEHP
310 320 330 340 350 360
ENPLWIGIDC GIVGTLNRED KRYLAENFLA FFNRDYRRVA ELHVESGWVP PDTKVDEFEF
370 380 390 400 410 420
AIRTVLEPIF EKPLSEISFG HVLLNLFNTA RRFNMQVQPQ LVLLQKTLLY VEGLGRQLYP
430 440 450 460 470 480
QLDLWQTAKP YLENWMYQQV GPKAVWNAIK EKAPFWAEKL PELPELVYET LRQTRHQQRH
490 500 510 520 530 540
FDQMFADFRR HSRRQGQARY LLGVGASLLL AGVFLLTQKQ HIEWGQISLA GAGLCWLLGW
LRTRSH