A0JMY4

PR
Gene name
ccdc176 (bbof1)
Protein name
Basal body-orientation factor 1
Names
Coiled-coil domain-containing protein 176
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:100036788
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-65 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0JMY4

Entry ID Method Resolution Chain Position Source
AF-A0JMY4-F1 Predicted AlphaFoldDB

No variants for A0JMY4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0JMY4

No associated diseases with A0JMY4

7 regional properties for A0JMY4

Type Name Position InterPro Accession
repeat Leucine-rich repeat 180 - 201 IPR001611-1
repeat Leucine-rich repeat 203 - 224 IPR001611-2
repeat Leucine-rich repeat, typical subtype 178 - 200 IPR003591-1
repeat Leucine-rich repeat, typical subtype 201 - 223 IPR003591-2
repeat Leucine-rich repeat, typical subtype 224 - 247 IPR003591-3
domain Endonuclease/exonuclease/phosphatase 312 - 649 IPR005135
repeat Leucine rich repeat 4 181 - 218 IPR025875

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, cilium basal body
  • Localizes to a polar structure adjacent to the basal body
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ciliary basal body A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
motile cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKLKVKAGK GKKGKRKKAG KNEHRLDKES EVERARSNAA LWEARLKVTE FSRVEYRDAA
70 80 90 100 110 120
RSLAQNNEDL TKQQYKLEKD MVEVIGFLKK QDLEKDELIE KLQQNLIAQK KSAQDEREKL
130 140 150 160 170 180
VELYSKQIAH LEENYSQKTN EMQIIQSEFK LMREFRRQKV ELEKELDEVK ESLWRANQDH
190 200 210 220 230 240
KETLARMERR FFEEKQRLEK EAEKKIMMLA EKAHSEAIIQ LDEARKSVFK ENVRLKEAFS
250 260 270 280 290 300
YHLKEMKDIK KSKKMQEDAK LHLLQEKETN DLLVQEKVSQ VSQKKVQIQE LQQNVKALEC
310 320 330 340 350 360
ALERMTMEME KDAQGKEHQA LLQEQAGNVE LQKLQKVLHM KEREMNRIKK LARNILEERT
370 380 390 400 410 420
EVESFFLEAL WQVKQEIATS RNYYRQVAQS AYTSKMIQAS LGKDQYPKIR TFHNKEHSTN
430 440 450 460 470 480
DVSHDLSEAE KWTHIQAGKV DIGDLTWEQK EKVLRLLFAK MNGFQSRKSP GLKPSPPADV
490 500 510 520 530
SSIKEKEINT SNLEEKPEES SSTFITQSIP ELPAPSLVLP HIQTGRCQVT G