A0JMP0

PR
Gene name
pgghg
Protein name
Protein-glucosylgalactosylhydroxylysine glucosidase
Names
Acid trehalase-like protein 1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:777617
EC number
3.2.1.107: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

59-142 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0JMP0

Entry ID Method Resolution Chain Position Source
AF-A0JMP0-F1 Predicted AlphaFoldDB

No variants for A0JMP0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0JMP0

No associated diseases with A0JMP0

1 regional properties for A0JMP0

Type Name Position InterPro Accession
domain Glycoside hydrolase, family 65, central catalytic 246 - 450 IPR005195

Functions

Description
EC Number 3.2.1.107 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.
protein-glucosylgalactosylhydroxylysine glucosidase activity Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.

1 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGGVYNGDGG TCHRGNIPCP LAAQMKTGEV GRQLYELNMH TGVFSHTVVT SDFEAIQVLY
70 80 90 100 110 120
AHRNQSNLLV MEILLKRIKT SAEPITIQLE SSFKPQSEDI AFQNAPDYKG GRHIFGQTAS
130 140 150 160 170 180
SEVPGGVRPV VHLIWTPVTP TLTLPANQSQ SSWTFLVAVA RSNESAQSFY DSGLALINTG
190 200 210 220 230 240
DLRPSHQRSW AELWKGSSIE VIGAESLNRA LIGCMFYLLG SFPYVNKEAS AAFEFGGVSP
250 260 270 280 290 300
GGLSNGSEDE DYHGHVFWDQ DTWMYPSIAL FYPALARAVL QYRVETLEGA QVNAQQMGCK
310 320 330 340 350 360
GLKFAWESAV TGVDVCPEDV YSQQELHING DVILAFQQYY YLTQDLELFQ SGRGSEVVWG
370 380 390 400 410 420
VADFWVSRVT WDSADQQYHI KGVIPPDEYY FTVDNSVFTN AVAQRSLEFA VELSALLAEV
430 440 450 460 470 480
PPPAWQDIAD KIKIPFDPEL KFHPEFDGYK PGNKVKQADV VLLGFPLAFP MSPEIRRNDL
490 500 510 520 530 540
EMYEAVTDPL GPAMTWGMFA LGWLELGEAE KAQKLLQKCF KNVQKPFQVW SESADGSGCV
550 560 570 580 590 600
NFLTGMGGFL QAVLFGYTGF RVQKEQLAFS PLLPLDVSAL SVKGVCYLGH KMDWTITSEE
610 620 630 640 650
VKVSVRKTDS KETFTLQVVL NSGSTLLLTP GQSVSFPRQP GHICQLKSSS SCWPI