A0B688

PR
Gene name
priS
Protein name
DNA primase small subunit PriS
Names
Species
Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanosaeta thermophila)
KEGG Pathway
mtp:Mthe_0420
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

209-285 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0B688

Entry ID Method Resolution Chain Position Source
AF-A0B688-F1 Predicted AlphaFoldDB

No variants for A0B688

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0B688

No associated diseases with A0B688

No regional properties for A0B688

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A0B688

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.
primosome complex Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.

2 GO annotations of molecular function

Name Definition
DNA primase activity Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MESKTSTYLR ARFREYYLTA SMDAPPGMEA REWGFIFYDT PGMRRHRSFR SRKELVDYIR
70 80 90 100 110 120
STVPAHVYHS AAYYLKPDAP TMKEKIWKGA DLIFDLDADH LAEYRGSGIR DFREMLERVK
130 140 150 160 170 180
GETMKLLEFL LSDFGFDERM ISVAFSGGRG YHIHVRDKSV LKLRSDARRE IVDYLTGRGL
190 200 210 220 230 240
DPERFIHKIG VDGDAGVERA RSLRGPASDA PGWGGRINKA IESMVMHLRE LDDEEALRLL
250 260 270 280 290 300
KNVKGIGKQK ARLFLSQIRE ENAIKSIRAG NLDFFKHASG IWNLIIPYIM EETVRALGGE
310 320 330 340 350 360
TDEPVTADVH RLIRFPESLH GGTGLRVTSL SINSLHAFDP LKDAVVFGDD PVHVEIIRPT
370 380 390
TLELMGERFD LLEGKTELPE YAAVFLLARG FAEVG