A0AL52

PR
Gene name
pgi
Protein name
Glucose-6-phosphate isomerase
Names
GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI
Species
Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / CIP 8149 / NCTC 11857 / SLCC 5334 / V8)
KEGG Pathway
lwe:lwe2316
EC number
5.3.1.9: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

404-450 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A0AL52

Entry ID Method Resolution Chain Position Source
AF-A0AL52-F1 Predicted AlphaFoldDB

No variants for A0AL52

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A0AL52

No associated diseases with A0AL52

8 regional properties for A0AL52

Type Name Position InterPro Accession
domain Histidine kinase/HSP90-like ATPase 338 - 446 IPR003594
domain HAMP domain 174 - 233 IPR003660
domain Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 232 - 293 IPR003661
domain Signal transduction histidine kinase-related protein, C-terminal 375 - 389 IPR004358-1
domain Signal transduction histidine kinase-related protein, C-terminal 393 - 403 IPR004358-2
domain Signal transduction histidine kinase-related protein, C-terminal 407 - 425 IPR004358-3
domain Histidine kinase domain 241 - 446 IPR005467
domain Two-component histidine kinase, sensor domain 38 - 148 IPR031930

Functions

Description
EC Number 5.3.1.9 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
carbohydrate derivative binding Binding to a carbohydrate derivative.
glucose-6-phosphate isomerase activity Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.

2 GO annotations of biological process

Name Definition
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTHIKFDYSK ALRFFEEREL DYLEPAVKAA HDSLHNGTGA GNDALGWINL PTDYDKEEFA
70 80 90 100 110 120
RIKKATEKIH SDSDVLIVIG IGGSYLGARA AIETLNHSFY NVLEKGARKT PQVFFAGNSI
130 140 150 160 170 180
SSSYLHDLIE VVGDRDFSVN VISKSGTTTE PAIAFRVFKE LLIKKYGEEG AKKRIYATTD
190 200 210 220 230 240
KAKGALKTLS DNEGYETFVV PDDVGGRFSV LTAVGLLPIA VSGVDIDALM NGARAASKDF
250 260 270 280 290 300
DKPELKNNIS YQYAAARNVL YRKGKVTELL ISYEPGLQYL NEWWKQLFGE SEGKDKKGIY
310 320 330 340 350 360
PSSANFSTDL HSIGQYIQDG RRNLFETVIK VDKPRHNLTI NKEEVDLDGL NYLAGETVDF
370 380 390 400 410 420
VNTKAFEGTL LAHTDGEVPN FVVEVPELDA YTFGYLVYFF EKAVAISGYL NGVNPFDQPG
430 440
VEAYKANMFA LLGKPGFEDK KAELEKRLND